Cell membranes contain a large variety of lipid types and are crowded with proteins,
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …

Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …

Natural genetic variation in the human genome is a cause of individual differences in
responses to medications and is an underappreciated burden on public health. Although …

Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

To execute their many vital functions, cell membranes are highly organized. Here, we review
how membrane structure shapes signal transduction across membranes. Recent …

Cholesterol, an essential molecule for cell structure, function, and viability, plays crucial
roles in the development, progression, and survival of cancer cells. Earlier studies have …

The serine/threonine kinase Akt is a master regulator of many diverse cellular functions,
including survival, growth, metabolism, migration, and differentiation. Receptor tyrosine …

The endocannabinoid system (ECS) has been placed in the anti-cancer spotlight in the last
decade. The immense data load published on its dual role in both tumorigenesis and …

Omega‐3 (ω‐3) fatty acids (FA s) such as docosahexaenoic acid (DHA) and
eicosapentaenoic acid (EPA) are known to have important roles in human health and …

G protein coupled receptors (GPCRs) are a class of membrane proteins that sense
extracellular signals ranging from light to odorants and small molecules and activate …