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Anesthesia and the develo** brain: a review of sevoflurane-induced neurotoxicity in pediatric populations
C Apai, R Shah, K Tran, SP Shah - Clinical therapeutics, 2021 - Elsevier
Purpose For over 150 years of anesthetic practice, it was believed that the effects of general
anesthetics were temporary and not adverse. A growing number of studies over the past 2 …
anesthetics were temporary and not adverse. A growing number of studies over the past 2 …
Neurotoxicity of anesthetics: Mechanisms and meaning from mouse intervention studies
Volatile anesthetics are widely used in human medicine and generally considered to be safe
in healthy individuals. In recent years, the safety of volatile anesthesia in pediatric patients …
in healthy individuals. In recent years, the safety of volatile anesthesia in pediatric patients …
Cognitive impairment and transcriptomic profile in hippocampus of young mice after multiple neonatal exposures to sevoflurane
SY Song, XW Meng, ZY ** rat brain against the neurotoxicity wrought by sevoflurane: role of autophagy and Drp1–Bax signaling
Y Shan, S Sun, F Yang, N Shang… - Drug design, development …, 2018 - Taylor & Francis
Background The effect of sevoflurane on the nervous system is controversial. As an adjuvant
anesthetic, dexmedetomidine has a protective role in various nerve-injury diseases. We …
anesthetic, dexmedetomidine has a protective role in various nerve-injury diseases. We …
Role of histone acetylation in long-term neurobehavioral effects of neonatal Exposure to sevoflurane in rats
M Jia, WX Liu, JJ Yang, N Xu, ZM ** brain has attracted much …
Sevoflurane exposure during the critical period affects synaptic transmission and mitochondrial respiration but not long-term behavior in mice.
Background Anesthesia during the synaptogenic period induces dendritic spine formation,
which may affect neurodevelopment. The authors, therefore, evaluated whether changes in …
which may affect neurodevelopment. The authors, therefore, evaluated whether changes in …