Trypanosoma brucei provides an excellent system for studies of many aspects of cell
biology, including cell structure and morphology, organelle positioning, cell division and …

Trypanosoma brucei is a pathogenic unicellular eukaryote that infects humans and other
mammals in sub-Saharan Africa. A central feature of trypanosome biology is the single …

Trypanosoma brucei is a model trypanosomatid, an important group of human, animal and
plant unicellular parasites. Understanding their complex cell architecture and life cycle is …

Double-stranded RNA (dsRNA) recently has been shown to give rise to genetic interference
in Caenorhabditis elegans and also is likely to be the basis for phenotypic cosuppression in …

To gain insight into the process of mitochondrial transmission in yeast, we directly labeled
mitochondrial proteins and mitochondrial DNA (mtDNA) and observed their fate after the …

In Kinetoplastida, trypanothione and trypanothione reductase (TRYR) provide an
intracellular reducing environment, substituting for the glutathione–glutathione reductase …

Trypanosomes are important disease agents and excellent models for the study of
evolutionary cell biology. The trypanosome flagellar pocket is a small invagination of the …

The cell cycle is central to understanding fundamental biology of Leishmania, a group of
human‐infective protozoan parasites. Leishmania have two main life cycle morphologies …

▪ Abstract Species of the trypanosomatid parasite genera Trypanosoma and Leishmania
exhibit a particular range of cell shapes that are defined by their internal cytoskeletons. The …

Trypanosomes possess a single flagellum that is attached to their cell body via the flagellum
attachment zone (FAZ). The FAZ is composed of two structures: a cytoplasmic filament …