New-generation vaccines, formulated with subunits or nucleic acids, are less immunogenic
than classical vaccines formulated with live-attenuated or inactivated pathogens. This …

Summary Interleukin-22 (IL-22) is a vital cytokine that is dysregulated in various autoimmune
conditions including rheumatoid arthritis (RA), multiple sclerosis (MS), and Alzheimer's …

The innate immune system facilitates defense mechanisms against pathogen invasion and
cell damage. Toll-like receptors (TLRs) assist in the activation of the innate immune system …

Primary and adaptive resistance to immune checkpoint therapies (ICT) represent a
considerable obstacle to achieving enhanced overall survival. Innate immune activators …

Abstract Ligustri Lucidi Fructus is a dried and mature fruit of Ligustrum lucidum Ait., which
has the effects of nourishing liver and kidney. Herein, an accurate and sensitive method was …

Background/Aim: The small intestine is one of the organs most vulnerable to ionizing
radiation (IR) damage. However, methods to protect against IR-induced intestinal injury are …

Background/Aim: CBLB502, a Toll-like receptor-5 agonist derived from Salmonella flagellin,
exerts protective roles against irradiation and chemical drugs in mammalian tissues and …

Ischemia-reperfusion injury (IRI) is a common complication of surgery, which can cause
rapid deterioration of the liver function, increase the risk of graft rejection, and seriously …

Sepsis is the leading systemic inflammatory response syndrome in worldwide, yet relatively
little is known about the genes and signaling pathways involved in sepsis progression. The …

Cystic fibrosis (CF) is one of the inherited autosomal recessive disorders with very
complicated pathogenesis. Identifying the molecular signatures and specific biomarkers of …