Microneedles for drug and vaccine delivery

YC Kim, JH Park, MR Prausnitz - Advanced drug delivery reviews, 2012‏ - Elsevier
Microneedles were first conceptualized for drug delivery many decades ago, but only
became the subject of significant research starting in the mid-1990's when microfabrication …

Microneedle-based drug delivery systems: microfabrication, drug delivery, and safety

RF Donnelly, TRR Singh, AD Woolfson - Drug delivery, 2010‏ - Taylor & Francis
Many promising therapeutic agents are limited by their inability to reach the systemic
circulation, due to the excellent barrier properties of biological membranes, such as the …

Hydrogel‐forming microneedle arrays for enhanced transdermal drug delivery

RF Donnelly, TRR Singh, MJ Garland… - Advanced functional …, 2012‏ - Wiley Online Library
Unique microneedle arrays prepared from crosslinked polymers, which contain no drug
themselves, are described. They rapidly take up skin interstitial fluid upon skin insertion to …

Ultrasound mediated transdermal drug delivery

A Azagury, L Khoury, G Enden, J Kost - Advanced drug delivery reviews, 2014‏ - Elsevier
Transdermal drug delivery offers an attractive alternative to the conventional drug delivery
methods of oral administration and injections. However, the stratum corneum serves as a …

Microneedles for drug delivery: trends and progress

K Cheung, DB Das - Drug delivery, 2016‏ - Taylor & Francis
In recent years, there has been a surge in the research and development of microneedles
(MNs), a transdermal delivery system that combines the technology of transdermal patches …

[HTML][HTML] Nanosuspension-based dissolving microneedle arrays for intradermal delivery of curcumin

S Abdelghany, IA Tekko, L Vora, E Larrañeta… - Pharmaceutics, 2019‏ - mdpi.com
The objective of this study was to evaluate the intradermal delivery of curcumin utilising poly
(vinylalcohol)(PVA)-based microneedles loaded with curcumin nanosuspension (CU-NS) …

Recent progress of 3D-printed microneedles for transdermal drug delivery

Q Yang, W Zhong, L Xu, H Li, Q Yan, Y She… - International Journal of …, 2021‏ - Elsevier
Microneedles as novel transdermal drug delivery systems have lately attracted extensive
attention due to their distinguished properties, including improved patient compliance and …

Recent advances in microneedle composites for biomedical applications: Advanced drug delivery technologies

S Sharma, K Hatware, P Bhadane, S Sindhikar… - Materials Science and …, 2019‏ - Elsevier
In the twenty-first century, microneedles based drug delivery is drawing attention worldwide
in the research due to current signs of progress in the controlled release drug delivery …

Hydrogel-forming microneedle arrays made from light-responsive materials for on-demand transdermal drug delivery

JG Hardy, E Larrañeta, RF Donnelly… - Molecular …, 2016‏ - ACS Publications
We describe, for the first time, stimulus-responsive hydrogel-forming microneedle (MN)
arrays that enable delivery of a clinically relevant model drug (ibuprofen) upon application of …

Stimuli-responsive polymer microneedles: A rising transdermal drug delivery system and Its applications in biomedical

R Liu, A Li, Y Lang, H Cai, X Tang, D Li, X Liu… - Journal of Drug Delivery …, 2023‏ - Elsevier
Microneedles (MNs) are a novel transdermal drug delivery technique that penetrate the skin
stratum corneum and deliver drugs to the target site, which are safer and more effective than …