Egypt's COVID-19 recent happenings and perspectives: a mini-review

ARA Saied, AA Metwally, NAB Madkhali… - Frontiers in Public …, 2021‏ - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has affected countries across the world. While the …

[HTML][HTML] Addressing Africa's pandemic puzzle: Perspectives on COVID-19 transmission and mortality in sub-Saharan Africa

HH Musa, TH Musa, IH Musa, IH Musa… - International Journal of …, 2021‏ - Elsevier
Abstract To date, SARS-CoV-2 (the virus that causes COVID-19) has spread to almost every
region of the world, infecting millions and resulting in the deaths of hundreds of thousands of …

Transferability of genetic risk scores in African populations

AB Kamiza, SM Toure, M Vujkovic, T Machipisa… - Nature Medicine, 2022‏ - nature.com
The poor transferability of genetic risk scores (GRSs) derived from European ancestry data
in diverse populations is a cause of concern. We set out to evaluate whether GRSs derived …

Variant PADI3 in Central Centrifugal Cicatricial Alopecia

L Malki, O Sarig, MT Romano, MC Méchin… - … England Journal of …, 2019‏ - Mass Medical Soc
Background Central centrifugal cicatricial alopecia (CCCA) is the most common form of
scarring alopecia among women of African ancestry. The disease is occasionally observed …

Biobanking with genetics shapes precision medicine and global health

CS Gallagher, GS Ginsburg, A Musick - Nature Reviews Genetics, 2024‏ - nature.com
Precision medicine provides patients with access to personally tailored treatments based on
individual-level data. However, develo** personalized therapies requires analyses with …

Adaptation to high altitude: phenotypes and genotypes

CM Beall - Annual Review of Anthropology, 2014‏ - annualreviews.org
Populations residing for millennia on the high-altitude plateaus of the world started natural
experiments that we can evaluate to address questions about the processes of evolution …

Nutrition and its role in human evolution

WPT James, RJ Johnson, JR Speakman… - Journal of internal …, 2019‏ - Wiley Online Library
Our understanding of human evolution has improved rapidly over recent decades, facilitated
by large‐scale cataloguing of genomic variability amongst both modern and archaic …

Five priorities of African genomics research: the next frontier

A Wonkam, NS Munung, C Dandara… - Annual Review of …, 2022‏ - annualreviews.org
To embrace the prospects of accurately diagnosing thousands of monogenic conditions,
predicting disease risks for complex traits or diseases, tailoring treatment to individuals' …

Genetic contributions to prostate cancer disparities in men of West African descent

JR Johnson, L Woods-Burnham, SE Hooker Jr… - Frontiers in …, 2021‏ - frontiersin.org
Prostate cancer (PCa) is the second most frequently diagnosed malignancy and the second
leading cause of death in men worldwide, after adjusting for age. According to the …

Considerations for cardiovascular genetic and genomic research with marginalized racial and ethnic groups and indigenous peoples: a scientific statement from the …

G Mudd-Martin, AL Cirino, V Barcelona… - Circulation: Genomic …, 2021‏ - ahajournals.org
Historically marginalized racial and ethnic groups and Indigenous peoples are burdened by
significant health inequities that are compounded by their underrepresentation in genetic …