Decellularized extracellular matrix: new promising and challenging biomaterials for regenerative medicine

M Brown, J Li, C Moraes, M Tabrizian, NYK Li-Jessen - Biomaterials, 2022 - Elsevier
Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …

Contribution of extracellular vesicles for the pathogenesis of retinal diseases: Shedding light on blood-retinal barrier dysfunction

B Martins, M Pires, AF Ambrósio, H Girão… - Journal of Biomedical …, 2024 - Springer
Retinal degenerative diseases, including diabetic retinopathy (DR) and age-related macular
degeneration (AMD), loom as threats to vision, causing detrimental effects on the structure …

Size matters: Functional differences of small extracellular vesicle subpopulations in cardiac repair responses

SI van de Wakker, J Bauzá‐Martinez… - Journal of …, 2024 - Wiley Online Library
Cardiac progenitor cell (CPC)‐derived small extracellular vesicles (sEVs) exhibit great
potential to stimulate cardiac repair. However, the multifaceted nature of sEV heterogeneity …

[HTML][HTML] Isolation of Aloe saponaria-Derived Extracellular Vesicles and Investigation of Their Potential for Chronic Wound Healing

M Kim, JH Park - Pharmaceutics, 2022 - mdpi.com
A chronic wound is caused by a failure to progress through the normal phases of wound
repair in an orderly and timely manner. To induce skin regeneration while inhibiting chronic …

Annexin A5 derived from matrix vesicles protects against osteoporotic bone loss via mineralization

G Su, D Zhang, T Li, T Pei, J Yang, S Tu, S Liu, J Ren… - Bone Research, 2023 - nature.com
Matrix vesicles (MVs) have shown strong effects in diseases such as vascular ectopic
calcification and pathological calcified osteoarthritis and in wound repair of the skeletal …

Tumor cell membrane‐based vaccines: A potential boost for cancer immunotherapy

M Yang, J Zhou, L Lu, D Deng, J Huang, Z Tang… - …, 2024 - Wiley Online Library
Because therapeutic cancer vaccines can, in theory, eliminate tumor cells specifically with
relatively low toxicity, they have long been considered for application in repressing cancer …

[HTML][HTML] HYDRHA: Hydrogels of hyaluronic acid. New biomedical approaches in cancer, neurodegenerative diseases, and tissue engineering

M Grieco, O Ursini, IE Palama, G Gigli, L Moroni… - Materials Today Bio, 2022 - Elsevier
In the last decade, hyaluronic acid (HA) has attracted an ever-growing interest in the
biomedical engineering field as a biocompatible, biodegradable, and chemically versatile …

Optimizing cell therapy by sorting cells with high extracellular vesicle secretion

D Koo, X Cheng, S Udani, S Baghdasarian… - Nature …, 2024 - nature.com
Critical challenges remain in clinical translation of extracellular vesicle (EV)-based
therapeutics due to the absence of methods to enrich cells with high EV secretion. Current …

[HTML][HTML] Advances in purification, modification, and application of extracellular vesicles for novel clinical treatments

Y Matsuzaka, R Yashiro - Membranes, 2022 - mdpi.com
Extracellular vesicles (EV) are membrane vesicles surrounded by a lipid bilayer membrane
and include microvesicles, apoptotic bodies, exosomes, and exomeres. Exosome …

[HTML][HTML] Extracellular vesicles on the move: Traversing the complex matrix of tissues

S Arif, VJ Moulin - European journal of cell biology, 2023 - Elsevier
Extracellular vesicles are small particles involved in intercellular signaling. They are
produced by virtually all cell types, transport biological molecules, and are released into the …