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Decellularized extracellular matrix: new promising and challenging biomaterials for regenerative medicine
Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …
glycosaminoglycans, and small molecules that are important for the maintenance and repair …
Contribution of extracellular vesicles for the pathogenesis of retinal diseases: Shedding light on blood-retinal barrier dysfunction
Retinal degenerative diseases, including diabetic retinopathy (DR) and age-related macular
degeneration (AMD), loom as threats to vision, causing detrimental effects on the structure …
degeneration (AMD), loom as threats to vision, causing detrimental effects on the structure …
Size matters: Functional differences of small extracellular vesicle subpopulations in cardiac repair responses
SI van de Wakker, J Bauzá‐Martinez… - Journal of …, 2024 - Wiley Online Library
Cardiac progenitor cell (CPC)‐derived small extracellular vesicles (sEVs) exhibit great
potential to stimulate cardiac repair. However, the multifaceted nature of sEV heterogeneity …
potential to stimulate cardiac repair. However, the multifaceted nature of sEV heterogeneity …
[HTML][HTML] Isolation of Aloe saponaria-Derived Extracellular Vesicles and Investigation of Their Potential for Chronic Wound Healing
M Kim, JH Park - Pharmaceutics, 2022 - mdpi.com
A chronic wound is caused by a failure to progress through the normal phases of wound
repair in an orderly and timely manner. To induce skin regeneration while inhibiting chronic …
repair in an orderly and timely manner. To induce skin regeneration while inhibiting chronic …
Annexin A5 derived from matrix vesicles protects against osteoporotic bone loss via mineralization
G Su, D Zhang, T Li, T Pei, J Yang, S Tu, S Liu, J Ren… - Bone Research, 2023 - nature.com
Matrix vesicles (MVs) have shown strong effects in diseases such as vascular ectopic
calcification and pathological calcified osteoarthritis and in wound repair of the skeletal …
calcification and pathological calcified osteoarthritis and in wound repair of the skeletal …
Tumor cell membrane‐based vaccines: A potential boost for cancer immunotherapy
Because therapeutic cancer vaccines can, in theory, eliminate tumor cells specifically with
relatively low toxicity, they have long been considered for application in repressing cancer …
relatively low toxicity, they have long been considered for application in repressing cancer …
[HTML][HTML] HYDRHA: Hydrogels of hyaluronic acid. New biomedical approaches in cancer, neurodegenerative diseases, and tissue engineering
In the last decade, hyaluronic acid (HA) has attracted an ever-growing interest in the
biomedical engineering field as a biocompatible, biodegradable, and chemically versatile …
biomedical engineering field as a biocompatible, biodegradable, and chemically versatile …
Optimizing cell therapy by sorting cells with high extracellular vesicle secretion
Critical challenges remain in clinical translation of extracellular vesicle (EV)-based
therapeutics due to the absence of methods to enrich cells with high EV secretion. Current …
therapeutics due to the absence of methods to enrich cells with high EV secretion. Current …
[HTML][HTML] Advances in purification, modification, and application of extracellular vesicles for novel clinical treatments
Y Matsuzaka, R Yashiro - Membranes, 2022 - mdpi.com
Extracellular vesicles (EV) are membrane vesicles surrounded by a lipid bilayer membrane
and include microvesicles, apoptotic bodies, exosomes, and exomeres. Exosome …
and include microvesicles, apoptotic bodies, exosomes, and exomeres. Exosome …
[HTML][HTML] Extracellular vesicles on the move: Traversing the complex matrix of tissues
Extracellular vesicles are small particles involved in intercellular signaling. They are
produced by virtually all cell types, transport biological molecules, and are released into the …
produced by virtually all cell types, transport biological molecules, and are released into the …