Paramagnetic chemical probes have been used in electron paramagnetic resonance (EPR)
and nuclear magnetic resonance (NMR) spectroscopy for more than four decades. Recent …

The biological function of protein, DNA, and RNA molecules often depends on relative
movements of domains with dimensions of a few nanometers. This length scale can be …

Electron paramagnetic resonance (EPR) spectroscopy provides a variety of tools to study
structures and structural changes of large biomolecules or complexes thereof. In order to …

Pulsed ESR techniques with the aid of site-directed spin labeling have proven useful in
providing unique structural information about proteins. The determination of distance …

Resolving the nanometer-scale structure of biomolecules in natural conditions still remains a
challenging task. We report the first distance measurement in nucleic acid at physiological …

In a lot of cases active biomolecules are complexes of higher order, thus methods capable of
counting the number of building blocks and elucidating their geometric arrangement are …

The tertiary structure and conformational dynamics of ribonucleic acids (RNAs) are essential
for their function as biological catalysts, regulators, and structural scaffolds.[1] X-ray …

We used EPR spectroscopy to characterize the structure of RNA duplexes and their internal
twist, stretch and bending motions. We prepared eight 20‐base‐pair‐long RNA duplexes …

A pulsed electron paramagnetic resonance (EPR) spectroscopic ruler for oligonucleotides
was developed using a series of duplex DNAs. The spin-labeling is accomplished during …

Pulse electron− electron double resonance distance measurements between two high spin
Gd3+ ions in a novel bis-Gd3+ complex involving two pyridine-based gadolinium …