Metabolic reprogramming is an important cancer hallmark that plays a key role in cancer
malignancies and therapy resistance. Cancer cells reprogram the metabolic pathways to …

Cancer progression is a multifaceted process that entails several stages and demands the
persistent expression or activation of transcription factors (TFs) to facilitate growth and …

Background Airborne fine particulate matter (PM2. 5) has been associated with lung cancer
development and progression in never smokers. However, the molecular mechanisms …

Moonlighting proteins are defined as proteins with two or more functions that are unrelated
and independent to each other, so that inactivation of one of them should not affect the …

Transcription and translation are fundamental cellular processes that govern the protein
production of cells. These processes are generally up regulated in cancer cells, to maintain …

LHPP, a histidine phosphatase, has been implicated in tumour progression. However, its
role, underlying mechanisms, and prognostic significance in human gastric cancer (GC) are …

Background Expression of the KITENIN/ErbB4 oncogenic complex is associated with
metastasis of colorectal cancer to distant organs and lymph nodes and is linked with poor …

Proteins are the most common types of biomarkers used in breast cancer (BC) theranostics
and management. By definition, a biomarker must be a relevant, objective, stable, and …

Abstract Background Prostate cancer (PCa) is the second most prevalent cancer in males
worldwide, yet detecting PCa and its metastases remains a major challenging task in clinical …

The purpose of this study was to characterize the expression of procollagen-lysine, 2-
oxoglutarate 5-dioxygenase 2 (PLOD2), a membrane-bound homodimeric enzyme that …