Recent advances in berberine inspired anticancer approaches: from drug combination to novel formulation technology and derivatization

S Habtemariam - Molecules, 2020 - mdpi.com
Berberine is multifunctional natural product with potential to treat diverse pathological
conditions. Its broad-spectrum anticancer effect through direct effect on cancer cell growth …

Histone acetyltransferase inhibitors: An overview in synthesis, structure-activity relationship and molecular mechanism

M Huang, J Huang, Y Zheng, Q Sun - European Journal of Medicinal …, 2019 - Elsevier
Acetylation, a key component in post-translational modification regulated by HATs and
HDACs, is relevant to many crucial cellular contexts in organisms. Based on crucial …

[BOOK][B] Silver Catalysis in Organic Synthesis, 2 Volume Set

CJ Li, X Bi - 2019 - books.google.com
Covers all the aspects of the recent achievements in silver catalyzed reactions Silver
catalysis has emerged as a powerful tool in the field of organic synthesis. This …

Berberine: a promising natural isoquinoline alkaloid for the development of hypolipidemic drugs

DD Li, P Yu, W **ao, ZZ Wang… - Current Topics in …, 2020 - ingentaconnect.com
Berberine, as a representative isoquinoline alkaloid, exhibits significant hypolipidemic
activity in both animal models and clinical trials. Recently, a large number of studies on the …

Novel inhibitors of an insect pest chitinase: design and optimization of 9-O-aromatic and heterocyclic esters of berberine

L Zhu, L Chen, X Shao, J Cheng… - Journal of Agricultural …, 2021 - ACS Publications
Of Chi-h, a lepidopteran-exclusive glycoside hydrolase family 18 (GH18) chitinase from the
agricultural insect pest Ostrinia furnacalis, is a promising molecular target candidate for pest …

Natural STAT3 inhibitors: A mini perspective

Z Wang, C Hui, Y **e - Bioorganic Chemistry, 2021 - Elsevier
Signal transducer and activator of transcription 3 (STAT3) plays pivotal role in several
cellular processes such as cell proliferation and survival and has been found to be …

Gold-Catalyzed Ammonium Acetate Assisted Cascade Cyclization of 2-Alkynylarylketones

ME Domaradzki, Y Long, Z She, X Liu… - The Journal of …, 2015 - ACS Publications
An ammonium acetate assisted gold-catalyzed cascade cyclization reaction of 2-
alkynylarylketones is described. Under the reported conditions, a gold-catalyzed …

Ten years of progress in the synthesis of six-membered N-heterocycles from alkynes and nitrogen sources

JSS Neto, G Zeni - Tetrahedron, 2020 - Elsevier
The purpose of this review is to highlight ten years of success in the synthesis of six-
membered N-heterocycles using alkynes and nitrogen sources as substrates. It is our hope …

Concise total syntheses of berberine and its analogues enabled by trifluoroacetic anhydride-promoted decarbonylative-elimination reaction

X Yan, J Zheng, WDZ Li - Tetrahedron Letters, 2023 - Elsevier
The total syntheses of berberine hydrochloride and its analogues were achieved by a
convergent strategy from available meconine derivatives, which were based on base …

Rh-Catalyzed Ortho C–H Alkynylation of Aromatic Aldehydes

E Tan, LJ Nannini, O Stoica, AM Echavarren - Organic Letters, 2021 - ACS Publications
The Rh (III)-catalyzed ortho-alkynylation of benzaldehydes is enabled by the transient
formation of an imine as a directing group. A broad scope of substrates was obtained under …