Multi-criteria optimization and decision-making in radiotherapy

S Breedveld, D Craft, R Van Haveren… - European Journal of …, 2019‏ - Elsevier
Radiotherapy (radiation therapy) is one of the main treatments for cancer. The aim is to
deliver a prescribed radiation dose to the tumor, while kee** the unavoidable dose to the …

Artificial intelligence‐based radiotherapy machine parameter optimization using reinforcement learning

WT Hrinivich, J Lee - Medical physics, 2020‏ - Wiley Online Library
Purpose To develop and evaluate a volumetric modulated arc therapy (VMAT) machine
parameter optimization (MPO) approach based on deep‐Q reinforcement learning (RL) …

Clinical VMAT machine parameter optimization for localized prostate cancer using deep reinforcement learning

WT Hrinivich, M Bhattacharya, L Mekki… - Medical …, 2024‏ - Wiley Online Library
Background Volumetric modulated arc therapy (VMAT) machine parameter optimization
(MPO) remains computationally expensive and sensitive to input dose objectives creating …

System and method for learning models of radiotherapy treatment plans to predict radiotherapy dose distributions

LS Hibbard - US Patent 11,850,445, 2023‏ - Google Patents
US11850445B2 - System and method for learning models of radiotherapy treatment plans
to predict radiotherapy dose distributions - Google Patents US11850445B2 - System and …

Automated and clinically optimal treatment planning for cancer radiotherapy

M Zarepisheh, L Hong, Y Zhou… - … journal on applied …, 2022‏ - pubsonline.informs.org
Each year, approximately 18 million new cancer cases are diagnosed worldwide, and about
half must be treated with radiotherapy. A successful treatment requires treatment planning …

Multi-agent reinforcement learning meets leaf sequencing in radiotherapy

R Gao, FC Ghesu, S Arberet, S Basiri… - arxiv preprint arxiv …, 2024‏ - arxiv.org
In contemporary radiotherapy planning (RTP), a key module leaf sequencing is
predominantly addressed by optimization-based approaches. In this paper, we propose a …

Development of an autonomous treatment planning strategy for radiation therapy with effective use of population‐based prior data

H Wang, P Dong, H Liu, L **ng - Medical physics, 2017‏ - Wiley Online Library
Purpose Current treatment planning remains a costly and labor intensive procedure and
requires multiple trial‐and‐error adjustments of system parameters such as the weighting …

Optimization of combined proton–photon treatments

J Unkelbach, M Bangert, KDA Bernstein… - Radiotherapy and …, 2018‏ - Elsevier
Purpose Proton treatment slots are a limited resource. Therefore, we consider combined
proton–photon treatments in which most fractions are delivered with photons and only a few …

Radiation therapy of synchronous bilateral breast carcinoma (SBBC) using multiple techniques

SJ Kim, MJ Lee, SM Youn - Medical dosimetry, 2018‏ - Elsevier
The purpose of this study was to establish intensity-modulated radiation therapy (IMRT) and
volumetric-modulated arc therapy (VMAT) treatment plans for synchronous bilateral breast …

On mixed electron–photon radiation therapy optimization using the column generation approach

MA Renaud, M Serban, J Seuntjens - Medical physics, 2017‏ - Wiley Online Library
Purpose Despite considerable increase in the number of degrees of freedom handled by
recent radiotherapy optimisation algorithms, treatments are still typically delivered using a …