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Obesity, adipose tissue and vascular dysfunction
Cardiovascular diseases are the leading cause of death worldwide. Overweight and obesity
are strongly associated with comorbidities such as hypertension and insulin resistance …
are strongly associated with comorbidities such as hypertension and insulin resistance …
Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …
Adipose tissue distribution and morphology play a key role in determining the degree of …
Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities
Obesity is a major risk factor for cardiometabolic diseases. Nevertheless, a substantial
proportion of individuals with obesity do not suffer cardiometabolic comorbidities. The …
proportion of individuals with obesity do not suffer cardiometabolic comorbidities. The …
The role of obesity-induced perivascular adipose tissue (PVAT) dysfunction in vascular homeostasis
Perivascular adipose tissue (PVAT) is an additional special type of adipose tissue
surrounding blood vessels. Under physiological conditions, PVAT plays a significant role in …
surrounding blood vessels. Under physiological conditions, PVAT plays a significant role in …
Perivascular adipose tissue regulates vascular function by targeting vascular smooth muscle cells
Adipose tissues are present at multiple locations in the body. Most blood vessels are
surrounded with adipose tissue which is referred to as perivascular adipose tissue (PVAT) …
surrounded with adipose tissue which is referred to as perivascular adipose tissue (PVAT) …
Perivascular adipose tissue and vascular smooth muscle tone: friends or foes?
Perivascular adipose tissue (PVAT) is a specialized type of adipose tissue that surrounds
most mammalian blood vessels. PVAT is a metabolically active, endocrine organ capable of …
most mammalian blood vessels. PVAT is a metabolically active, endocrine organ capable of …
Coronary microvascular dysfunction
S Godo, A Suda, J Takahashi, S Yasuda… - … , and vascular biology, 2021 - ahajournals.org
Over the past couple of decades, accumulating evidence has shown that structural and
functional abnormalities of coronary microvasculature are highly prevalent, associated with …
functional abnormalities of coronary microvasculature are highly prevalent, associated with …
The pathobiology of perivascular adipose tissue (PVAT), the fourth layer of the blood vessel wall
C Hillock-Watling, AI Gotlieb - Cardiovascular Pathology, 2022 - Elsevier
The perivascular adipose tissue (PVAT) is an adipose tissue depot which surrounds most
human blood vessels. It is metabolically active and has both a protective and a pathogenic …
human blood vessels. It is metabolically active and has both a protective and a pathogenic …
[HTML][HTML] Role of perivascular adipose tissue-derived adiponectin in vascular homeostasis
Studies of adipose tissue biology have demonstrated that adipose tissue should be
considered as both passive, energy-storing tissue and an endocrine organ because of the …
considered as both passive, energy-storing tissue and an endocrine organ because of the …
Roles of perivascular adipose tissue in hypertension and atherosclerosis
Significance: Perivascular adipose tissue (PVAT), which is present surrounding most blood
vessels, from the aorta to the microvasculature of the dermis, is mainly composed of fat cells …
vessels, from the aorta to the microvasculature of the dermis, is mainly composed of fat cells …