The drug discovery process starts with identification of a disease-modifying target. This
critical step traditionally begins with manual investigation of scientific literature and …

Computational drug repurposing has the ability to remarkably reduce drug development
time and cost in an era where these factors are prohibitively high. Several examples of …

The stria vascularis (SV) generates the endocochlear potential (EP) in the inner ear and is
necessary for proper hair cell mechanotransduction and hearing. While channels belonging …

The extent to which genetic variations contribute to interindividual differences in weight loss
and metabolic outcomes after bariatric surgery is unknown. Identifying genetic variants that …

Drug development is a very costly and lengthy process, while repositioned or repurposed
drugs could be brought into clinical practice within a shorter time-frame and at a much …

Introduction: The use of semantic web technologies to aid drug discovery has gained
momentum over recent years. Researchers in this domain have realized that semantic web …

Target prioritization is essential for drug discovery and repositioning. Applying
computational methods to analyze and process multi-omics data to find new drug targets is a …

Background Drug development is still a costly and time-consuming process with a low rate
of success. Drug repurposing (DR) has attracted significant attention because of its …

Drug repositioning refers to the identification of new therapeutic indications for drugs already
approved. Albendazole and ricobendazole have been used as anti-parasitic drugs for many …

Different diseases can be treated with various therapeutic agents. Drug discovery aims to
find potential molecules for existing and emerging diseases. However, factors, such as …