Background Migraine is a highly prevalent primary headache disorder. Despite a high
burden of disease, key disease mechanisms are not entirely understood. Functional …

Objectives To comprehensively summarize and meta-analyze the concurrence across voxel-
based morphometric (VBM) neuroimaging studies of migraine. Methods Neuroimaging …

We examined cell type-specific expression and distribution of rat brain angiotensin-
converting enzyme 2 (ACE2), the receptor for SARS-CoV-2, in the rodent brain. ACE2 is …

Background New daily persistent headache (NPDH) is a rare primary headache that is
highly disabling. The pathophysiology of NDPH is still unclear, and we aimed to reveal the …

Exploring changes in the intrinsic activity of the brain in people with bipolar disorder (BD) is
necessary. However, the findings have not yet led to consistent conclusions. In this regard …

Background Migraine involves central and peripheral nervous system mechanisms.
Erenumab, an anti-calcitonin gene-related peptide (CGRP) receptor monoclonal antibody …

Objectives To quantitatively summarize the specific changes in brain structure and function
in migraine patients. Methods A literature screening of migraine was conducted from …

Neuroimaging studies have demonstrated that migraine is accompanied by spontaneous
brain activity alterations in specific regions. However, these findings are inconsistent, thus …

The noradrenergic theory of Cognitive Reserve (Robertson, 2013–2014) postulates that the
upregulation of the locus coeruleus—noradrenergic system (LC–NA) originating in the …

Neuroimaging is a powerful tool to investigate potential associations between chronic pain
and brain structure. However, the proliferation of studies across diverse chronic pain …