Mitochondrial genetics through the lens of single-cell multi-omics

L Nitsch, CA Lareau, LS Ludwig - Nature genetics, 2024 - nature.com
Mitochondria carry their own genetic information encoding for a subset of protein-coding
genes and translational machinery essential for cellular respiration and metabolism. Despite …

Role of reactive oxygen species in aging and age-related diseases: A review

MI Anik, N Mahmud, AA Masud, MI Khan… - ACS Applied Bio …, 2022 - ACS Publications
Research on the role of reactive oxygen species (ROS) in the aging process has advanced
significantly over the last two decades. In light of recent findings, ROS takes part in the aging …

Detection of ultra-rare mutations by next-generation sequencing

MW Schmitt, SR Kennedy, JJ Salk… - Proceedings of the …, 2012 - National Acad Sciences
Next-generation DNA sequencing promises to revolutionize clinical medicine and basic
research. However, while this technology has the capacity to generate hundreds of billions …

Molecular Poltergeists: Mitochondrial DNA Copies (numts) in Sequenced Nuclear Genomes

E Hazkani-Covo, RM Zeller, W Martin - PLoS genetics, 2010 - journals.plos.org
The natural transfer of DNA from mitochondria to the nucleus generates nuclear copies of
mitochondrial DNA (numts) and is an ongoing evolutionary process, as genome sequences …

Time‐dependent rates of molecular evolution

SYW Ho, R Lanfear, L Bromham, MJ Phillips… - Molecular …, 2011 - Wiley Online Library
For over half a century, it has been known that the rate of morphological evolution appears
to vary with the time frame of measurement. Rates of microevolutionary change, measured …

A lethal mitonuclear incompatibility in complex I of natural hybrids

BM Moran, CY Payne, DL Powell, ENK Iverson… - Nature, 2024 - nature.com
The evolution of reproductive barriers is the first step in the formation of new species and
can help us understand the diversification of life on Earth. These reproductive barriers often …

Wolbachia Variants Induce Differential Protection to Viruses in Drosophila melanogaster: A Phenotypic and Phylogenomic Analysis

E Chrostek, MSP Marialva, SS Esteves… - PLoS …, 2013 - journals.plos.org
Wolbachia are intracellular bacterial symbionts that are able to protect various insect hosts
from viral infections. This tripartite interaction was initially described in Drosophila …

Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA

B Rebolledo-Jaramillo, MSW Su… - Proceedings of the …, 2014 - National Acad Sciences
The manifestation of mitochondrial DNA (mtDNA) diseases depends on the frequency of
heteroplasmy (the presence of several alleles in an individual), yet its transmission across …

Inference on population history and model checking using DNA sequence and microsatellite data with the software DIYABC (v1. 0)

JM Cornuet, V Ravigné, A Estoup - BMC bioinformatics, 2010 - Springer
Abstract Background Approximate Bayesian computation (ABC) is a recent flexible class of
Monte-Carlo algorithms increasingly used to make model-based inference on complex …

Argasid and ixodid systematics: implications for soft tick evolution and systematics, with a new argasid species list

BJ Mans, J Featherston, M Kvas, KA Pillay… - Ticks and tick-borne …, 2019 - Elsevier
The systematics of the genera and subgenera within the soft tick family Argasidae is not
adequately resolved. Different classification schemes, reflecting diverse schools of scientific …