Over millions of years, vertebrate species populated vast environments spanning the globe.
Among the most challenging habitats encountered were those with limited availability of …

Humans and other mammals inhabit hypoxic high-altitude locales. In many of these species,
genes under positive selection include ones in the Hypoxia Inducible Factor (HIF) pathway …

Cattle pastoralism plays a central role in human livelihood in Africa. However, the genetic
history of its success remains unknown. Here, through whole-genome sequence analysis of …

Inbred animals were historically chosen for genome analysis to circumvent assembly issues
caused by haplotype variation but this resulted in a composite of the two genomes. Here we …

The blue wildebeest (Connochaetes taurinus) is a keystone species in savanna ecosystems
from southern to eastern Africa, and is well known for its spectacular migrations and locally …

Bovine viral diarrhea virus (BVDV) is one of the most important viruses affecting the health
and well-being of bovine species throughout the world. Here, we used CRISPR-mediated …

Next-generation sequencing has yielded a vast amount of cattle genomic data for global
characterization of population genetic diversity and identification of genomic regions under …

Background The development of trio binning as an approach for assembling diploid
genomes has enabled the creation of fully haplotype-resolved reference genomes. Unlike …

Cattle are an important livestock species, and map** the genomic architecture of
agriculturally relevant traits such as disease susceptibility is a major challenge in the bovine …

Background Bovine congestive heart failure (BCHF) has become increasingly prevalent
among feedlot cattle in the Western Great Plains of North America with up to 7% mortality in …