Chronic inflammation is a known risk factor for gastrointestinal cancer. The evidence that
nonsteroidal anti-inflammatory drugs suppress the incidence, growth, and metastasis of …

Chronic inflammation is a risk factor for gastrointestinal cancer and other diseases. Most
studies have focused on cytokines and chemokines as mediators connecting chronic …

Regular, long-term aspirin use may act synergistically with genetic variants, particularly
those in mechanistically relevant pathways, to confer a protective effect on colorectal cancer …

Macrophage polarization is mainly steered by metabolic reprogramming in the tissue
microenvironment, thus leading to distinct outcomes of various diseases. However, the role …

High-quality evidence indicates that regular use of aspirin is effective in reducing the risk for
precancerous colorectal neoplasia and colorectal cancer (CRC). This has led to US and …

Mounting evidence from preclinical and clinical studies suggests that persistent
inflammation functions as a driving force in the journey to cancer. Cyclooxygenase-2 (COX …

The tumor immune microenvironment plays a vital role in the metastasis of colorectal cancer.
As one of the most important immune cells, macrophages act as phagocytes, patrol the …

Background In the present study, we aim to investigate the potential role of propofol in the
tumor progression of colon cancer. Methods Human colon cancer cell lines were cultured …

In normal colon tissue, oestrogen receptor alpha (ERα) is expressed at low levels, while
oestrogen receptor beta (ERβ) is considered the dominant subtype. However, in colon …

Ethnopharmacological relevance Qi deficiency liver cancer (QDLC) is an important part of
liver cancer research in traditional Chinese medicine (TCM). In the course of its treatment …