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The global burden of sepsis: barriers and potential solutions
Sepsis is a major contributor to the global burden of disease. The majority of sepsis cases
and deaths are estimated to occur in low and middle-income countries. Barriers to reducing …
and deaths are estimated to occur in low and middle-income countries. Barriers to reducing …
The global problem of childhood diarrhoeal diseases: emerging strategies in prevention and management
M Mokomane, I Kasvosve, E Melo… - Therapeutic …, 2018 - journals.sagepub.com
Acute diarrhoeal diseases remain a leading cause of global morbidity and mortality
particularly among young children in resource-limited countries. Recent large studies …
particularly among young children in resource-limited countries. Recent large studies …
[HTML][HTML] Childhood pneumonia in low-and-middle-income countries: an update
Objectives To review epidemiology, aetiology and management of childhood pneumonia in
low-and-middle-income countries. Design Review of published English literature between …
low-and-middle-income countries. Design Review of published English literature between …
Global case-fatality rates in pediatric severe sepsis and septic shock: a systematic review and meta-analysis
Importance The global patterns and distribution of case-fatality rates (CFRs) in pediatric
severe sepsis and septic shock remain poorly described. Objective We performed a …
severe sepsis and septic shock remain poorly described. Objective We performed a …
A core outcome set for pediatric critical care
Objectives: More children are surviving critical illness but are at risk of residual or new health
conditions. An evidence-informed and stakeholder-recommended core outcome set is …
conditions. An evidence-informed and stakeholder-recommended core outcome set is …
Daily co-trimoxazole prophylaxis to prevent mortality in children with complicated severe acute malnutrition: a multicentre, double-blind, randomised placebo …
Background Children with complicated severe acute malnutrition (SAM) have a greatly
increased risk of mortality from infections while in hospital and after discharge. In HIV …
increased risk of mortality from infections while in hospital and after discharge. In HIV …
Acute kidney injury, persistent kidney disease, and post-discharge morbidity and mortality in severe malaria in children: a prospective cohort study
Background Globally, 85% of acute kidney injury (AKI) cases occur in low-and-middle-
income countries. There is limited information on persistent kidney disease (acute kidney …
income countries. There is limited information on persistent kidney disease (acute kidney …
Biomarkers of post-discharge mortality among children with complicated severe acute malnutrition
High mortality after discharge from hospital following acute illness has been observed
among children with Severe Acute Malnutrition (SAM). However, mechanisms that may be …
among children with Severe Acute Malnutrition (SAM). However, mechanisms that may be …
Paediatric postdischarge mortality in develo** countries: a systematic review
Objectives To update the current evidence base on paediatric postdischarge mortality (PDM)
in develo** countries. Secondary objectives included an evaluation of risk factors, timing …
in develo** countries. Secondary objectives included an evaluation of risk factors, timing …
Mortality after inpatient treatment for severe pneumonia in children: a cohort study
Background Although pneumonia is a leading cause of inpatient mortality, deaths may also
occur after discharge from hospital. However, prior studies have been small, in selected …
occur after discharge from hospital. However, prior studies have been small, in selected …