High-throughput methods in the discovery and study of biomaterials and materiobiology

L Yang, S Pijuan-Galito, HS Rho, AS Vasilevich… - Chemical …, 2021 - ACS Publications
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

[HTML][HTML] The role of stiffness in cell reprogramming: a potential role for biomaterials in inducing tissue regeneration

M d'Angelo, E Benedetti, MG Tupone, M Catanesi… - Cells, 2019 - mdpi.com
The mechanotransduction is the process by which cells sense mechanical stimuli such as
elasticity, viscosity, and nanotopography of extracellular matrix and translate them into …

Hierarchically hybrid biocoatings on Ti implants for enhanced antibacterial activity and osteogenesis

Z Wang, L Mei, X Liu, Q Zhou - Colloids and Surfaces B: Biointerfaces, 2021 - Elsevier
Highlights•Hierarchically hybrid CS/nHA-nZnO-PDA coating on Ti implants is successfully
developed.•The developed Ti-based implants exhibit enhanced antibacterial efficacy.•The …

Effects of bone surface topography and chemistry on macrophage polarization

B Özcolak, B Erenay, S Odabaş, KD Jandt… - Scientific reports, 2024 - nature.com
Surface structure plays a crucial role in determining cell behavior on biomaterials,
influencing cell adhesion, proliferation, differentiation, as well as immune cells and …

Unidirectional rotating molecular motors dynamically interact with adsorbed proteins to direct the fate of mesenchymal stem cells

Q Zhou, J Chen, Y Luan, PA Vainikka, S Thallmair… - Science …, 2020 - science.org
Artificial rotary molecular motors convert energy into controlled motion and drive a system
out of equilibrium with molecular precision. The molecular motion is harnessed to mediate …

Electrospun nanofiber blend with improved mechanical and biological performance

AO Lobo, S Afewerki, MMM De Paula… - International journal …, 2018 - Taylor & Francis
Background Here, electrospun fibers based on a blend of polycaprolactone (PCL), poly
(ethylene glycol)(PEG), and gelatin methacryloyl (GelMA) were developed. The careful …

Molecular and biomechanical clues from cardiac tissue decellularized extracellular matrix drive stromal cell plasticity

GR Liguori, TTA Liguori, SR de Moraes… - … in bioengineering and …, 2020 - frontiersin.org
Decellularized-organ-derived extracellular matrix (dECM) has been used for many years in
tissue engineering and regenerative medicine. The manufacturing of hydrogels from dECM …

Osteogenic and anti-inflammatory effect of the multifunctional bionic hydrogel scaffold loaded with aspirin and nano-hydroxyapatite

S Li, Y **aowen, Y Yang, L Liu, Y Sun, Y Liu… - … in Bioengineering and …, 2023 - frontiersin.org
Although tissue engineering offered new approaches to repair bone defects, it remains a
great challenge to create a bone-friendly microenvironment and rebuild bone tissue rapidly …

Screening platform for cell contact guidance based on inorganic biomaterial micro/nanotopographical gradients

Q Zhou, O Castañeda Ocampo… - … applied materials & …, 2017 - ACS Publications
High-throughput screening (HTS) methods based on topography gradients or arrays have
been extensively used to investigate cell–material interactions. However, it is a huge …

Biomaterial surface energy-driven ligand assembly strongly regulates stem cell mechanosensitivity and fate on very soft substrates

T Razafiarison, CN Holenstein, T Stauber… - Proceedings of the …, 2018 - pnas.org
Although mechanisms of cell–material interaction and cellular mechanotransduction are
increasingly understood, the mechanical insensitivity of mesenchymal cells to certain soft …