Microsatellite instability (MSI) refers to the hypermutator phenotype secondary to frequent
polymorphism in short repetitive DNA sequences and single nucleotide substitution, as …

Microsatellite instability (MSI), the spontaneous loss or gain of nucleotides from repetitive
DNA tracts, is a diagnostic phenotype for gastrointestinal, endometrial, and colorectal …

Short tandem repeats (STRs) are some of the fastest mutating loci in the genome. Tools for
accurately profiling STRs from high-throughput sequencing data have enabled genome …

Thyroid cancer is the most common malignancy of the endocrine system. The diagnosis of
thyroid nodules, made by neck examination and ultrasonography, is a common event …

Background: Inactivation of DNA mismatch repair (MMR) and the resulting microsatellite
instability (MSI) are frequently observed in endometrial, stomach, and colorectal cancers, as …

Microsatellite instability (MSI), the spontaneous loss or gain of nucleotides from repetitive
DNA tracts, is a diagnostic phenotype for gastrointestinal, endometrial, colorectal, and …

Background Mutations in DNA mismatch repair (MMR) genes associated with thyroid
carcinoma (TC) have rarely been reported, especially in East Asian populations. Methods …

Results Selected citations revealed the prevalence of MSI in 7.4%, with mutations in the
MSH2 gene (33%) being the most frequent, followed by MSH6 (25%) and MLH1 (16.7%) …

Genetic instability (GI) is a hallmark feature of tumor development. Securin, also known as
pituitary tumor transforming gene (PTTG), is a mitotic checkpoint protein which is highly …

Thyroid cancer's incidence has increased by leaps and bounds over the last years and
accounts for 2.8% of new cases of cancers. This increasing bar is partially assisted by …