Loss of tumor suppressor gene function in human cancer: an overview

LH Wang, CF Wu, N Rajasekaran… - Cellular Physiology and …, 2019 - karger.com
Cancer is a disease caused by the accumulation of genetic and epigenetic changes in two
types of genes: tumor suppressor genes (TSGs) and proto-oncogenes. Extensive research …

Cervical cancer markers: epigenetics and microRNAs

V Laengsri, U Kerdpin, C Plabplueng… - Laboratory …, 2018 - academic.oup.com
Gynecologic malignant neoplasms are a severe health problem among female patients, of
which cervical cancer (CC), in particular, is a common disease leading to high mortality …

Modulation of DNA methylation by human papillomavirus E6 and E7 oncoproteins in cervical cancer

P Sen, P Ganguly, N Ganguly - Oncology letters, 2018 - spandidos-publications.com
Human papillomaviruses (HPVs) are double stranded circular DNA viruses that infect
cutaneous and mucosal epithelial cells. Almost 99% of cervical cancer has a HPV infection …

[HTML][HTML] Repeated PM2. 5 exposure inhibits BEAS-2B cell P53 expression through ROS-Akt-DNMT3B pathway-mediated promoter hypermethylation

W Zhou, D Tian, J He, Y Wang, L Zhang, L Cui… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Long-term exposure to fine particulate matter (PM2. 5) has been reported to be closely
associated with the increased lung cancer risk in populations, but the mechanisms …

Epigenetic regulation in the pathogenesis of non-melanoma skin cancer

MP Kashyap, R Sinha, MS Mukhtar, M Athar - Seminars in cancer biology, 2022 - Elsevier
Understanding of cancer with the help of ever-expanding cutting edge technological tools
and bioinformatics is revolutionizing modern cancer research by broadening the space of …

MiRNA in cervical cancer: Diagnosis to therapy: Systematic review

HT Endale, YF Mariye, HK Negash, FS Hassen… - Heliyon, 2024 - cell.com
Cancers are one of the most public health problems worldwide. Among them, cervical
cancer (CC) is the fourth most prevalent cancer with 604 000 new cases and 342 000 …

Biological implications and therapeutic significance of DNA methylation regulated genes in cervical cancer

S Bhat, SP Kabekkodu, A Noronha, K Satyamoorthy - Biochimie, 2016 - Elsevier
Cervical cancer is the second most common cancer among women worldwide. About
528,000 women are diagnosed with cervical cancer contributing to around 266,000 deaths …

Putative biomarkers for cervical cancer: SNVs, methylation and expression profiles

MFS Cardoso, CHM Castelletti, JL de Lima-Filho… - … Research/Reviews in …, 2017 - Elsevier
Cervical cancer is primarily caused by Human papillomavirus (HPV) infection, but other
factors such as smoking habits, co-infections and genetic background, can also contribute to …

Determining the effect of DNA methylation on gene expression in cancer cells

CJ Lee, J Evans, K Kim, H Chae, S Kim - Gene Function Analysis, 2014 - Springer
DNA methylation, a DNA modification by adding methyl group to cytosine, has an important
role in the regulation of gene expression. DNA methylation is known to be associated with …

Aberrant DNA methylation of tumor suppressor genes and oncogenes as cancer biomarkers

E Alshammari, Y Zhang, J Sobota… - … of Toxicology and …, 2022 - Wiley Online Library
Epigenetic alterations play an essential role in the dysregulation of gene expression that
contribute to the pathogenesis of human cancers. As a major epigenetic modification …