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The role of inflammation in the pathogenesis of osteoarthritis
YY Chow, KY Chin - Mediators of inflammation, 2020 - Wiley Online Library
A joint is the point of connection between two bones in our body. Inflammation of the joint
leads to several diseases, including osteoarthritis, which is the concern of this review …
leads to several diseases, including osteoarthritis, which is the concern of this review …
Mesenchymal stem cell related therapies for cartilage lesions and osteoarthritis
R Zhang, J Ma, J Han, W Zhang… - American journal of …, 2019 - pmc.ncbi.nlm.nih.gov
Osteoarthritis (OA) is a common degenerative joint disease characterized by cartilage
degradation, synovitis, subchondral bone sclerosis and osteophyte formation. Current …
degradation, synovitis, subchondral bone sclerosis and osteophyte formation. Current …
Inflammatory mediators in osteoarthritis: A critical review of the state-of-the-art, current prospects, and future challenges
Osteoarthritis (OA) has traditionally been defined as a prototypical non-inflammatory
arthropathy, but today there is compelling evidence to suggest that it has an inflammatory …
arthropathy, but today there is compelling evidence to suggest that it has an inflammatory …
[HTML][HTML] Chondrocyte and mesenchymal stem cell-based therapies for cartilage repair in osteoarthritis and related orthopaedic conditions
Osteoarthritis (OA) represents a final and common pathway for all major traumatic insults to
synovial joints. OA is the most common form of degenerative joint disease and a major …
synovial joints. OA is the most common form of degenerative joint disease and a major …
Role of lubricin and boundary lubrication in the prevention of chondrocyte apoptosis
Osteoarthritis is a complex disease involving the mechanical breakdown of articular
cartilage in the presence of altered joint mechanics and chondrocyte death, but the …
cartilage in the presence of altered joint mechanics and chondrocyte death, but the …
Fisetin inhibits IL-1β-induced inflammatory response in human osteoarthritis chondrocytes through activating SIRT1 and attenuates the progression of osteoarthritis in …
W Zheng, Z Feng, S You, H Zhang, Z Tao… - International …, 2017 - Elsevier
Osteoarthritis (OA) is a degenerative joint disease characterized by cartilage degradation
and inflammation. Fisetin, a polyphenol extracted from fruits and vegetables, has been …
and inflammation. Fisetin, a polyphenol extracted from fruits and vegetables, has been …
Regulation of chondrocyte differentiation by the actin cytoskeleton and adhesive interactions
Chondrocyte differentiation is a multi‐step process characterized by successive changes in
cell morphology and gene expression. In addition to tight regulation by numerous soluble …
cell morphology and gene expression. In addition to tight regulation by numerous soluble …
Cell death of chondrocytes is a combination between apoptosis and autophagy during the pathogenesis of Osteoarthritis within an experimental model
M Almonte-Becerril, F Navarro-Garcia… - Apoptosis, 2010 - Springer
The death of chondrocytes and the loss of extracellular matrix are the central features in
cartilage degeneration during Osteoarthritis (OA) pathogenesis. The mechanism by which …
cartilage degeneration during Osteoarthritis (OA) pathogenesis. The mechanism by which …
Mesenchymal stem cells in regenerative medicine: opportunities and challenges for articular cartilage and intervertebral disc tissue engineering
SM Richardson, JA Hoyland… - Journal of cellular …, 2010 - Wiley Online Library
Defects of load‐bearing connective tissues such as articular cartilage and intervertebral disc
(IVD) can result from trauma, degenerative, endocrine, or age‐related disease. Current …
(IVD) can result from trauma, degenerative, endocrine, or age‐related disease. Current …
Protective effect of ginger (Zingiber officinale roscoe) extract against oxidative stress and mitochondrial apoptosis induced by interleukin-1β in cultured chondrocytes
Aims: The protective effects of ginger (Zingiber officinale Roscoe) extract on IL-1β-mediated
oxidative stress and mitochondrial apoptosis were investigated in C28I2 human …
oxidative stress and mitochondrial apoptosis were investigated in C28I2 human …