Alzheimer's disease (AD) is a highly heritable complex disease with no current effective
prevention or treatment. The majority of drugs developed for AD focus on the amyloid …

Genome-wide association studies and functional genomics studies have linked specific cell
types, genes, and pathways to Alzheimer's disease (AD) risk. In particular, AD risk alleles …

Aedes aegypti mosquitoes are a persistent human foe, transmitting arboviruses including
dengue when they feed on human blood. Mosquitoes are intensely attracted to body odor …

Microglia, the resident immune cells of the brain, rapidly change states in response to their
environment, but we lack molecular and functional signatures of different microglial …

Microglia play critical roles in brain development, homeostasis, and neurological disorders.
Here, we report that human microglial-like cells (iMGLs) can be differentiated from iPSCs to …

Odorants are detected as smell in the nasal epithelium of mammals by two G-protein-
coupled receptor families, the odorant receptors and the trace amine-associated …

The olfactory system is an ideal and tractable system for exploring how the brain transforms
sensory inputs into behaviour. The basic tasks of any olfactory system include odour …

The biological olfactory system is the sensory system responsible for the detection of the
chemical composition of the environment. Several attempts to mimic biological olfactory …

The plasma membrane tetraspan molecule MS4A4A is selectively expressed by
macrophage-lineage cells, but its function is unknown. Here we report that MS4A4A was …

Olfaction, the sense of smell detects and discriminate odors as well as social cues which
influence our innate responses. The olfactory system in human beings is found to be weak …