Ion mobility mass spectrometry (IM-MS) for structural biology: insights gained by measuring mass, charge, and collision cross section
E Christofi, P Barran - Chemical Reviews, 2023 - ACS Publications
The investigation of macromolecular biomolecules with ion mobility mass spectrometry (IM-
MS) techniques has provided substantial insights into the field of structural biology over the …
MS) techniques has provided substantial insights into the field of structural biology over the …
High-resolution native mass spectrometry
Native mass spectrometry (MS) involves the analysis and characterization of
macromolecules, predominantly intact proteins and protein complexes, whereby as much as …
macromolecules, predominantly intact proteins and protein complexes, whereby as much as …
Mass spectrometry using electrospray ionization
GRD Prabhu, ER Williams, M Wilm… - Nature Reviews Methods …, 2023 - nature.com
Applying a high voltage to a liquid passing through a capillary disintegrates the liquid
meniscus to generate a fine spray of charged droplets. As the droplets evaporate, polar …
meniscus to generate a fine spray of charged droplets. As the droplets evaporate, polar …
Perception and signaling of ultraviolet-B radiation in plants
Ultraviolet-B (UV-B) radiation is an intrinsic fraction of sunlight that plants perceive through
the UVR8 photoreceptor. UVR8 is a homodimer in its ground state that monomerizes upon …
the UVR8 photoreceptor. UVR8 is a homodimer in its ground state that monomerizes upon …
UV-B light and its application potential to reduce disease and pest incidence in crops
P Meyer, B Van de Poel, B De Coninck - Horticulture Research, 2021 - academic.oup.com
Abstract Ultraviolet-B radiation (280–315 nm), perceived by the plant photoreceptor UVR8,
is a key environmental signal that influences plant growth and development and can reduce …
is a key environmental signal that influences plant growth and development and can reduce …
Plant photoreceptors and their signaling components compete for COP 1 binding via VP peptide motifs
Plants sense different parts of the sun's light spectrum using distinct photoreceptors, which
signal through the E3 ubiquitin ligase COP 1. Here, we analyze why many COP 1 …
signal through the E3 ubiquitin ligase COP 1. Here, we analyze why many COP 1 …
Intrinsically disordered proteins play diverse roles in cell signaling
Signaling pathways allow cells to detect and respond to a wide variety of chemical (eg Ca2+
or chemokine proteins) and physical stimuli (eg, sheer stress, light). Together, these …
or chemokine proteins) and physical stimuli (eg, sheer stress, light). Together, these …
A constitutively monomeric UVR8 photoreceptor confers enhanced UV-B photomorphogenesis
The plant ultraviolet-B (UV-B) photoreceptor UVR8 plays an important role in UV-B
acclimation and survival. UV-B absorption by homodimeric UVR8 induces its …
acclimation and survival. UV-B absorption by homodimeric UVR8 induces its …
Exploring the structure and dynamics of macromolecular complexes by native mass spectrometry
Mass spectrometry (MS) is an effective approach for determining the mass of biomolecules
with high accuracy, sensitivity and speed. Over the past 25 years, MS performed under non …
with high accuracy, sensitivity and speed. Over the past 25 years, MS performed under non …
Dynamics and mechanism of dimer dissociation of photoreceptor UVR8
Photoreceptors are a class of light-sensing proteins with critical biological functions. UVR8 is
the only identified UV photoreceptor in plants and its dimer dissociation upon UV sensing …
the only identified UV photoreceptor in plants and its dimer dissociation upon UV sensing …