Virus infection can trigger extrinsic apoptosis. Cell-surface death receptors of the tumor
necrosis factor family mediate this process. They either assist persistent viral infection or …

In 2015, public awareness of Zika virus (ZIKV) rose in response to alarming statistics of
infants with microcephaly being born to women who were infected with the virus during …

Neurological complications affecting the central nervous system have been reported in adult
patients infected by Zika virus (ZIKV) but the underlying mechanisms remain unknown. Here …

We perform a CRISPR-Cas9 genome-wide screen in glioblastoma stem cells and identify
integrin αvβ5 as an internalization factor for Zika virus (ZIKV). Expression of αvβ5 is …

Zika virus is a mosquito-borne virus that is associated with neurodegenerative diseases,
including Guillain–Barré syndrome and congenital Zika syndrome. As Zika virus targets the …

Zika virus (ZIKV) is a strongly neurotropic flavivirus whose infection has been associated
with microcephaly in neonates. However, clinical and experimental evidence indicate that …

Zika virus (ZIKV) was first isolated in 1947. From its isolation until 2007, symptoms of ZIKV-
caused disease were limited (eg, fever, hives, and headache); however, during the epidemic …

Infection with the Zika virus (ZIKV), a member of the Flaviviridae family, can cause serious
neurological disorders, most notably microcephaly in newborns. In this study, we …

Zika virus (ZIKV) can lead to severe birth defects especially microcephaly in newborns by
infecting human neural progenitors and impairing brain development. However, as the …

Microglia, the resident macrophage of the central nervous system, are increasingly
recognized as contributing to diverse aspects of human development, health, and disease …