The collective activity of a population of neurons, beyond the properties of individual cells, is
crucial for many brain functions. A fundamental question is how activity correlations between …

In vivo two-photon calcium imaging (2PCI) is a technique used for recording neuronal
activity in the intact brain. It is based on the principle that, when neurons fire action …

It is typically assumed that large networks of neurons exhibit a large repertoire of nonlinear
behaviours. Here we challenge this assumption by leveraging mathematical models derived …

The brain's remarkable properties arise from the collective activity of millions of neurons.
Widespread application of dimensionality reduction to multi-neuron recordings implies that …

Human visual neurons rely on event-driven, energy-efficient spikes for communication, while
silicon image sensors do not. The energy-budget mismatch between biological systems and …

The breadth and complexity of natural behaviors inspires awe. Understanding how our
perceptions, actions, and internal thoughts arise from evolved circuits in the brain has …

Two-photon microscopy has enabled high-resolution imaging of neuroactivity at depth within
scattering brain tissue. However, its various realizations have not overcome the tradeoffs …

A central goal of neuroscience is to understand the representations formed by brain activity
patterns and their connection to behaviour. The classic approach is to investigate how …

Optogenetics ushered in a revolution in how neuroscientists interrogate brain function.
Because of technical limitations, the majority of optogenetic studies have used low spatial …

Recent progress in fluorescence imaging allows neuroscientists to observe the dynamics of
thousands of individual neurons, identified genetically or by their connectivity, across …