Oxidative stress results from the disruption of the redox system marked by a notable
overproduction of reactive oxygen species. There are four major sources of reactive oxygen …

Trimethylamine N-oxide (TMAO) is a biologically active gut microbiome-derived dietary
metabolite. Recent studies have shown that high circulating plasma TMAO levels are closely …

Chronic kidney disease (CKD) is a significant worldwide healthcare problem. Regardless of
the initial injury, renal fibrosis is the common final pathway leading to end stage renal …

The frequency of prediabetes is increasing as the prevalence of obesity rises worldwide. In
prediabetes, hyperglycemia, insulin resistance, and inflammation and metabolic …

Delaying pregnancy, which is on the rise, may increase the risk of cardiovascular disease in
both women and their children. The physiological mechanisms that lead to these effects are …

Maternal cardiovascular changes during pregnancy include an expansion of plasma
volume, increased cardiac output, decreased peripheral resistance, and increased …

Functional foods and their by-products contain a wide range of bioactive components with
an array of health benefits and were proposed to improve public health, well-being, and …

Successful pregnancy and reproduction are dependent on adequate uterine blood flow,
placental perfusion, and vascular responsivity to fetal demands. The ability to support …

Background: The autonomic nervous system (ANS) is known as a critical regulatory system
for pregnancy-induced adaptations. If it fails to function, life-threatening pregnancy …

Orange peel waste (OPW) is known to contain an abundant amount of polyphenols
compounds such as flavonoids, well-reported for their antioxidant and anti-inflammatory …