Water solubility and structural stability are key merits for proteins defined by the primary
sequence and 3D-conformation. Their manipulation represents important aspects of the …

Aromatic peptide amphiphiles are gaining popularity as building blocks for the bottom-up
fabrication of nanomaterials, including gels. These materials combine the simplicity of small …

Peptides that self-assemble into nanostructures are of tremendous interest for biological,
medical, photonic and nanotechnological applications. The enormous sequence space that …

Proteins are molecular machines whose function depends on their ability to achieve
complex folds with precisely defined structural and dynamic properties. The rational design …

Enzymes fold into unique three-dimensional structures, which underlie their remarkable
catalytic properties. The requirement to adopt a stable, folded conformation is likely to …

One of the hallmark advances in our understanding of metalloprotein function is showcased
in our ability to design new, non-native, catalytically active protein scaffolds. This review …

Self-assembly of molecules often results in new emerging properties. Even very short
peptides can self-assemble into structures with a variety of physical and structural …

Proteins at interfaces play important roles in cell biology, immunology, bioengineering, and
biomimetic material design. Many biological processes are based on interfacial protein …

In recent years, our understanding of protein structure and function has advanced rapidly,
providing a mechanistic understanding of a wide variety of biological processes. As an …

Self-replicating molecules are likely to have played an important role in the origin of life, and
a small number of fully synthetic self-replicators have already been described. Yet it remains …