Drug discovery is adapting to novel technologies such as data science, informatics, and
artificial intelligence (AI) to accelerate effective treatment development while reducing costs …

We report the main conclusions of the first Chemoinformatics and Artificial Intelligence
Colloquium, Mexico City, June 15–17, 2022. Fifteen lectures were presented during a virtual …

Background As global populations age and become susceptible to neurodegenerative
illnesses, new therapies for Alzheimer disease (AD) are urgently needed. Existing data …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive and
irreversible impairment of memory and other cognitive functions of the aging brain …

Alterations in the rate and accuracy of messenger RNA (mRNA) translation are associated
with aging and several neurodegenerative disorders, including Alzheimer's disease and …

Background Plant specialized (or secondary) metabolites (PSM), also known as
phytochemicals, natural products, or plant constituents, play essential roles in interactions …

Microglia are the earliest activated and the longest lasting immune cells after stroke, and
they participate in almost all the pathological reactions after stroke. However, their regulatory …

Background Dementia care is challenging due to the divergent trajectories in disease
progression and outcomes. Predictive models are needed to flag patients at risk of near-term …

The convergence of Artificial Intelligence (AI) and neuroscience is redefining our
understanding of the brain, unlocking new possibilities in research, diagnosis, and therapy …

Abstract Study Objectives Genetics impacts sleep, yet, the molecular mechanisms
underlying sleep regulation remain elusive. In this study, we built machine learning models …