Amplification-free CRISPR/Cas detection technology: challenges, strategies, and perspectives
Rapid and accurate molecular diagnosis is a prerequisite for precision medicine, food
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …
Functionalizing framework nucleic‐acid‐based nanostructures for biomedical application
T Zhang, T Tian, Y Lin - Advanced Materials, 2022 - Wiley Online Library
Strategies for functionalizing diverse tetrahedral framework nucleic acids (tFNAs) have been
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …
Rapid and ultrasensitive electromechanical detection of ions, biomolecules and SARS-CoV-2 RNA in unamplified samples
L Wang, X Wang, Y Wu, M Guo, C Gu, C Dai… - Nature Biomedical …, 2022 - nature.com
The detection of samples at ultralow concentrations (one to ten copies in 100 μl) in biofluids
is hampered by the orders-of-magnitude higher amounts of 'background'biomolecules. Here …
is hampered by the orders-of-magnitude higher amounts of 'background'biomolecules. Here …
DNA-framework-based multidimensional molecular classifiers for cancer diagnosis
A molecular classification of diseases that accurately reflects clinical behaviour lays the
foundation of precision medicine. The development of in silico classifiers coupled with …
foundation of precision medicine. The development of in silico classifiers coupled with …
2D semiconductors for specific electronic applications: from device to system
The shrinking of transistors has hit a wall of material degradation and the specialized
electronic applications for complex scenarios have raised challenges in heterostructures …
electronic applications for complex scenarios have raised challenges in heterostructures …
Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment
T Zhang, T Tian, R Zhou, S Li, W Ma, Y Zhang, N Liu… - Nature protocols, 2020 - nature.com
Although organic nanomaterials and inorganic nanoparticles possess inherent flexibility,
facilitating functional modification, increased intracellular uptake and controllable drug …
facilitating functional modification, increased intracellular uptake and controllable drug …
Nucleic acid tests for clinical translation
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …
natural biopolymers composed of nucleotides that store, transmit, and express genetic …
DNA walkers for biosensing development
L Song, Y Zhuge, X Zuo, M Li, F Wang - Advanced Science, 2022 - Wiley Online Library
The ability to design nanostructures with arbitrary shapes and controllable motions has
made DNA nanomaterials used widely to construct diverse nanomachines with various …
made DNA nanomaterials used widely to construct diverse nanomachines with various …
Isothermal amplification of nucleic acids
Isothermal amplification of nucleic acids is a simple process that rapidly and efficiently
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …
Biomolecular sensors for advanced physiological monitoring
Body-based biomolecular sensing systems, including wearable, implantable and
consumable sensors allow comprehensive health-related monitoring. Glucose sensors have …
consumable sensors allow comprehensive health-related monitoring. Glucose sensors have …