Osteoporosis is a major public health issue that is expected to rise as the global population
ages. Resveratrol (RES) is a plant polyphenol with various anti-aging properties. RES …

We used μCT and histomorphometry to assess age‐related changes in bone architecture in
male and female C57BL/6J mice. Deterioration in vertebral and femoral trabecular …

The objective of this study was to examine changes in the long bones of male C57BL/6J
mice with growth and aging, and to consider the applicability of this animal for use in …

Considerable scientific progress in the pathogenesis of vascular calcification that has
accrued in recent years is reviewed in this article. Factors regulating mesenchymal cell …

The purpose of this study was to evaluate the effects of sclerostin inhibition by treatment with
a sclerostin antibody (Scl‐AbII) on bone formation, bone mass, and bone strength in an …

In this study we present the analysis of in vivo micro-CT scans using a new method based
on image registration that accurately evaluates longitudinal micro-CT studies. We tested if …

Wrist and ankle fractures are the most frequent causes of complex regional pain syndrome
(CRPS type I). The current study examined the temporal development of vascular …

This investigation used capsaicin to selectively lesion unmyelinated sensory neurons in rats.
Neuronal lesioning induced a loss of trabecular integrity, reduced bone mass and strength …

Osteocyte is the orchestrator of bone remolding and decline in osteocyte autophagy is
involved in senile osteoporosis. Our results suggested that rapamycin, at least in part by …

BACKGROUND: Age-related bone loss is a primary factor in osteoporosis and osteoporotic
fractures in the elderly. Although oxidative stress was reported to play an important role in …