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Improved prediction of protein–protein interactions using novel negative samples, features, and an ensemble classifier
Computational methods are employed in bioinformatics to predict protein–protein
interactions (PPIs). PPIs and protein–protein non-interactions (PPNIs) display different levels …
interactions (PPIs). PPIs and protein–protein non-interactions (PPNIs) display different levels …
[SÁCH][B] Biomolecular networks: methods and applications in systems biology
Alternative techniques and tools for analyzing biomolecular networks With the recent rapid
advances in molecular biology, high-throughput experimental methods have resulted in …
advances in molecular biology, high-throughput experimental methods have resulted in …
[HTML][HTML] A high efficient biological language model for predicting protein–protein interactions
Many life activities and key functions in organisms are maintained by different types of
protein–protein interactions (PPIs). In order to accelerate the discovery of PPIs for different …
protein–protein interactions (PPIs). In order to accelerate the discovery of PPIs for different …
A pitfall for machine learning methods aiming to predict across cell types
Abstract Machine learning models that predict genomic activity are most useful when they
make accurate predictions across cell types. Here, we show that when the training and test …
make accurate predictions across cell types. Here, we show that when the training and test …
PCVMZM: using the probabilistic classification vector machines model combined with a zernike moments descriptor to predict protein–protein interactions from protein …
Protein–protein interactions (PPIs) are essential for most living organisms' process. Thus,
detecting PPIs is extremely important to understand the molecular mechanisms of biological …
detecting PPIs is extremely important to understand the molecular mechanisms of biological …
Computational models for prediction of protein–protein interaction in rice and Magnaporthe grisea
Introduction Plant–microbe interactions play a vital role in the development of strategies to
manage pathogen-induced destructive diseases that cause enormous crop losses every …
manage pathogen-induced destructive diseases that cause enormous crop losses every …
From protein-protein interactions to rational drug design: are computational methods up to the challenge?
The study of protein-protein interactions (PPIs) has been growing for some years now,
mainly as a result of easy access to high-throughput experimental data. Several …
mainly as a result of easy access to high-throughput experimental data. Several …
A new feature vector based on gene ontology terms for protein-protein interaction prediction
Protein-protein interaction (PPI) plays a key role in understanding cellular mechanisms in
different organisms. Many supervised classifiers like Random Forest (RF) and Support …
different organisms. Many supervised classifiers like Random Forest (RF) and Support …
Mining from protein–protein interactions
H Mamitsuka - Wiley Interdisciplinary Reviews: Data Mining and …, 2012 - Wiley Online Library
Proteins are important cellular molecules, and interacting protein pairs provide biologically
important information, such as functional relationships. We focus on the problem of …
important information, such as functional relationships. We focus on the problem of …
Predicting protein-protein interactions using high-quality non-interacting pairs
Background Identifying protein-protein interactions (PPIs) is of paramount importance for
understanding cellular processes. Machine learning-based approaches have been …
understanding cellular processes. Machine learning-based approaches have been …