Chemokine (C–X–C motif) ligand (CXCL) 10 in autoimmune diseases

A Antonelli, SM Ferrari, D Giuggioli, E Ferrannini… - Autoimmunity …, 2014 - Elsevier
Abstract (C–X–C motif) ligand (CXCL) 10 (CXCL10) belongs to the ELR− CXC subfamily
chemokine. CXCL10 exerts its function through binding to chemokine (C–X–C motif) …

Th1 chemokines in autoimmune endocrine disorders

P Fallahi, SM Ferrari, F Ragusa, I Ruffilli… - The Journal of …, 2020 - academic.oup.com
Context The CXC chemokine receptor CXCR3 and its chemokines CXCL10, CXCL9, and
CXCL11 are implicated in the pathogenesis of autoimmune diseases. Here, we review these …

CXCR3, CXCL10 and type 1 diabetes

A Antonelli, SM Ferrari, A Corrado, E Ferrannini… - Cytokine & growth factor …, 2014 - Elsevier
Abstract Type 1 diabetes (T1D) is due to antigen-specific assaults on the insulin producing
pancreatic β-cells by diabetogenic T-helper (Th) 1 cells.(CXC motif) ligand (CXCL) 10, an …

The change of serum tumor necrosis factor alpha in patients with type 1 diabetes mellitus: A systematic review and meta-analysis

Y Qiao, Y Chen, Y Pan, F Tian, Y Xu, X Zhang, H Zhao - PloS one, 2017 - journals.plos.org
Objective The aim of this study was used meta-analysis to investigate changes of serum
tumor necrosis factor-alpha (TNF-α) in patients with type 1 diabetes mellitus (T1DM) …

Comorbidity of allergic and autoimmune diseases among patients with ADHD: a nationwide population-based study

MH Chen, TP Su, YS Chen, JW Hsu… - Journal of attention …, 2017 - journals.sagepub.com
Objective: Patients with ADHD have been suggested to have increased risks of allergic
diseases but without consistent results, and limited studies about the association between …

Chemokines as drivers of the autoimmune destruction in type 1 diabetes: opportunity for therapeutic intervention in consideration of an optimal treatment schedule

U Christen, R Kimmel - Frontiers in endocrinology, 2020 - frontiersin.org
Type 1 diabetes (T1D) is mainly precipitated by the destruction of insulin-producing β-cells
in the pancreatic islets of Langerhans by autoaggressive T cells. The etiology of the disease …

Correlation between serum interleukin-6 level and type 1 diabetes mellitus: A systematic review and meta-analysis

YL Chen, YC Qiao, YH Pan, Y Xu, YC Huang… - Cytokine, 2017 - Elsevier
Objective This report aimed to explore the association between the change of circulating
interleukin-6 (IL-6) in patients and the development of type 1 diabetes mellitus (T1DM) …

Progress in immune-based therapies for type 1 diabetes

M Von Herrath, M Peakman… - Clinical & Experimental …, 2013 - academic.oup.com
Immune-based therapies that prevent type 1 diabetes or preserve metabolic function
remaining at diagnosis have become a major objective for funding agencies and …

Chemokines in type 1 diabetes mellitus

X Pan, AC Kaminga, S Kinra, SW Wen, H Liu… - Frontiers in …, 2022 - frontiersin.org
Background Previous studies suggested that chemokines may play an important role in the
formation and mediation of immune microenvironments of patients affected by Type 1 …

Serum Cytokines and Growth Factors in Subjects with Type 1 Diabetes: Associations with Time in Ranges and Glucose Variability

VV Klimontov, KR Mavlianova, NB Orlov, JF Semenova… - Biomedicines, 2023 - mdpi.com
The detrimental effect of hyperglycemia and glucose variability (GV) on target organs in
diabetes can be implemented through a wide network of regulatory peptides. In this study …