Throughout infancy, childhood, and adolescence, our brains undergo remarkable changes.
Processes including myelination and synaptogenesis occur rapidly across the first 2–3 years …

The use of the diffusion tensor imaging (DTI) is rapidly growing in the neuroimaging field.
Nevertheless, rigorously performed quantitative validation of DTI pathologic metrics remains …

The differentiation of neural stem cells (NSCs) into neurons is proposed to be critical in
devising potential cell-based therapeutic strategies for central nervous system (CNS) …

Alterations in white matter (WM) microstructure have been implicated in the pathophysiology
of major depressive disorder (MDD). However, previous findings have been inconsistent …

A growing preclinical and clinical body of work on the effects of chronic drug use and drug
addiction has extended the scope of inquiry from the putative reward-related subcortical …

Quantitative spinal cord (SC) magnetic resonance imaging (MRI) presents many challenges,
including a lack of standardized imaging protocols. Here we present a prospectively …

Dynamic macrostructural and microstructural changes take place from the mid-fetal stage to
2 years after birth. Delineating structural changes of the brain during early development …

Multiple sclerosis is characterized by inflammatory activity that results in destruction of the
myelin sheaths that enwrap axons. The currently available medications for multiple sclerosis …

Diffusion tensor imaging (DTI) has been used widely to show structural brain changes
during both development and aging. Lifespan studies are valuable because they connect …

Healthy human brain development is a complex process that continues during childhood
and adolescence, as demonstrated by many cross-sectional and several longitudinal …