Protocells: Milestones and recent advances

I Gözen, ES Köksal, I Põldsalu, L Xue, K Spustova… - Small, 2022 - Wiley Online Library
The origin of life is still one of humankind's great mysteries. At the transition between
nonliving and living matter, protocells, initially featureless aggregates of abiotic matter, gain …

Solar water sterilization enabled by photothermal nanomaterials

L Wang, Y Feng, K Wang, G Liu - Nano Energy, 2021 - Elsevier
Pathogen ingestion through drinking water bring about severe health threats to human
beings. Recently innovative nanotechnology and their integrated systems provide new …

The future of origin of life research: bridging decades-old divisions

M Preiner, S Asche, S Becker, HC Betts, A Boniface… - Life, 2020 - mdpi.com
Research on the origin of life is highly heterogeneous. After a peculiar historical
development, it still includes strongly opposed views which potentially hinder progress. In …

CO2 reduction driven by a pH gradient

R Hudson, R de Graaf… - Proceedings of the …, 2020 - National Acad Sciences
All life on Earth is built of organic molecules, so the primordial sources of reduced carbon
remain a major open question in studies of the origin of life. A variant of the alkaline …

Direct measuring of single–heterogeneous bubble nucleation mediated by surface topology

X Deng, Y Shan, X Meng, Z Yu, X Lu… - Proceedings of the …, 2022 - National Acad Sciences
Heterogeneous bubble nucleation is one of the most fundamental interfacial processes
ranging from nature to technology. There is excellent evidence that surface topology is …

Non-associative phase separation in an evaporating droplet as a model for prebiotic compartmentalization

W Guo, AB Kinghorn, Y Zhang, Q Li… - Nature …, 2021 - nature.com
The synthetic pathways of life's building blocks are envisaged to be through a series of
complex prebiotic reactions and processes. However, the strategy to compartmentalize and …

Division and regrowth of phase‐separated giant unilamellar vesicles

Y Dreher, K Jahnke, E Bobkova… - Angewandte Chemie …, 2021 - Wiley Online Library
Success in the bottom‐up assembly of synthetic cells will depend on strategies for the
division of protocellular compartments. Here, we describe the controlled division of phase …

Physical non-equilibria for prebiotic nucleic acid chemistry

A Ianeselli, A Salditt, C Mast, B Ercolano… - Nature Reviews …, 2023 - nature.com
The prebiotic replication of DNA and RNA is a complex interplay between chemistry and the
environment. Factors that have direct and indirect effects on prebiotic chemistry include …

RNA Oligomerisation without Added Catalyst from 2′, 3′‐Cyclic Nucleotides by Drying at Air‐Water Interfaces

AV Dass, S Wunnava, J Langlais… - …, 2023 - Wiley Online Library
For the emergence of life, the abiotic synthesis of RNA from its monomers is a central step.
We found that in alkaline, drying conditions in bulk and at heated air‐water interfaces, 2 …

Water cycles in a Hadean CO2 atmosphere drive the evolution of long DNA

A Ianeselli, M Atienza, PW Kudella, U Gerland… - Nature Physics, 2022 - nature.com
Dew is a common form of water that deposits from saturated air on colder surfaces. Although
presumably common on primordial Earth, its potential involvement in the origin of life in early …