Lipid nanoparticles for drug delivery

L Xu, X Wang, Y Liu, G Yang… - Advanced …, 2022 - Wiley Online Library
Lipid nanoparticles have attracted significant interests in the last two decades, and have
achieved tremendous clinical success since the first clinical approval of Doxil in 1995. At the …

Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology

C Domingues, A Santos, C Alvarez-Lorenzo… - ACS …, 2022 - ACS Publications
Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

Lipid nanoparticles as carriers for bioactive delivery

N Dhiman, R Awasthi, B Sharma, H Kharkwal… - Frontiers in …, 2021 - frontiersin.org
Nanotechnology has made a great impact on the pharmaceutical, biotechnology, food, and
cosmetics industries. More than 40% of the approved drugs are lipophilic and have poor …

Applications of nanosized-lipid-based drug delivery systems in wound care

AM Matei, C Caruntu, M Tampa, SR Georgescu… - Applied Sciences, 2021 - mdpi.com
Impaired wound healing is an encumbering public health issue that increases the demand
for develo** new therapies in order to minimize health costs and enhance treatment …

Incorporation of antibiotics into solid lipid nanoparticles: a promising approach to reduce antibiotic resistance emergence

L Arana, L Gallego, I Alkorta - Nanomaterials, 2021 - mdpi.com
Antimicrobial resistance is one of the biggest threats to global health as current antibiotics
are becoming useless against resistant infectious pathogens. Consequently, new …

[HTML][HTML] Multi-stimuli-responsive chitosan-functionalized magnetite/poly (ε-caprolactone) nanoparticles as theranostic platforms for combined tumor magnetic …

G García-García, C Caro, F Fernández-Álvarez… - … , Biology and Medicine, 2023 - Elsevier
Chitosan-functionalized magnetite/poly (ε-caprolactone) nanoparticles were formulated by
interfacial polymer disposition plus coacervation, and loaded with gemcitabine. That …

Nanomedicine at the crossroads–a quick guide for ivivc

MP Mast, H Modh, C Champanhac, JW Wang… - Advanced drug delivery …, 2021 - Elsevier
For many years, nanomedicine is pushing the boundaries of drug delivery. When applying
these novel therapeutics, safety considerations are not only a key concern when entering …

Chemistry and art of develo** lipid nanoparticles for biologics delivery: focus on development and scale-up

R John, J Monpara, S Swaminathan, R Kalhapure - Pharmaceutics, 2024 - mdpi.com
Lipid nanoparticles (LNPs) have gained prominence as primary carriers for delivering a
diverse array of therapeutic agents. Biological products have achieved a solid presence in …

[HTML][HTML] Mannose receptor targeted bioadhesive chitosan nanoparticles of clofazimine for effective therapy of tuberculosis

DM Pawde, MK Viswanadh, AK Mehata… - Saudi Pharmaceutical …, 2020 - Elsevier
Drug-resistant tuberculosis (TB) is one of the most lethal diseases, and it is imperative to
exploit an advanced drug formulation for its effective treatment. This work aims to develop a …

Lipid nanoparticles in topical dermal drug delivery: Does chemistry of lipid persuade skin penetration?

VGSS Jyothi, SM Ghouse, DK Khatri, S Nanduri… - Journal of Drug Delivery …, 2022 - Elsevier
Lipid nanostructures such as solid lipid nanoparticles (SLNs) and nanostructured lipid
carriers (NLCs) significantly fetched the attention of scientific fraternity owing to lucrative …