Rheumatoid arthritis (RA) is an autoimmune disease characterized by severe joint damage
and disability. However, the specific mechanism of RA has not been thoroughly clarified …

Nitric oxide (NO), a ubiquitous gaseous messenger, plays critical roles in various
pathological and physiological progresses. The abnormal levels of NO in organisms are …

The cytochrome P450 homolog, TxtE, efficiently catalyzes the direct and regioselective
aromatic nitration of the indolyl moiety of L‐tryptophan to 4‐nitro‐L‐tryptophan, using nitric …

Understanding electronic effects on catalysis from a mechanism point of view is of
fundamental significance but is also challenging. We herein report on electronic effects on …

Heme enzymes play a central role in a medley of reactivities within a wide variety of crucial
biological systems. Their active sites are highly decorated with pivotal evolutionarily …