Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia

E Connell, G Le Gall, MG Pontifex, S Sami… - Molecular …, 2022 - Springer
A consequence of our progressively ageing global population is the increasing prevalence
of worldwide age-related cognitive decline and dementia. In the absence of effective …

Ten Years of BrainAGE as a Neuroimaging Biomarker of Brain Aging: What Insights Have We Gained?

K Franke, C Gaser - Frontiers in neurology, 2019 - frontiersin.org
With the aging population, prevalence of neurodegenerative diseases is increasing, thus
placing a growing burden on individuals and the whole society. However, individual rates of …

[HTML][HTML] Cognitive profile following COVID-19 infection: Clinical predictors leading to neuropsychological impairment

M Almeria, JC Cejudo, J Sotoca, J Deus… - Brain, behavior, & …, 2020 - Elsevier
Background Cognitive manifestations associated with the severity of a novel coronavirus
(COVID-19) infection are unknown. An early detection of neuropsychological manifestations …

Predicting brain age with deep learning from raw imaging data results in a reliable and heritable biomarker

JH Cole, RPK Poudel, D Tsagkrasoulis, MWA Caan… - NeuroImage, 2017 - Elsevier
Abstract Machine learning analysis of neuroimaging data can accurately predict
chronological age in healthy people. Deviations from healthy brain ageing have been …

Brain age predicts mortality

JH Cole, SJ Ritchie, ME Bastin, V Hernández… - Molecular …, 2018 - nature.com
Age-associated disease and disability are placing a growing burden on society. However,
ageing does not affect people uniformly. Hence, markers of the underlying biological ageing …

[HTML][HTML] Memory aging and brain maintenance

L Nyberg, M Lövdén, K Riklund, U Lindenberger… - Trends in cognitive …, 2012 - cell.com
Episodic memory and working memory decline with advancing age. Nevertheless, large-
scale population-based studies document well-preserved memory functioning in some older …

Social and emotional aging

ST Charles, LL Carstensen - Annual review of psychology, 2010 - annualreviews.org
The past several decades have witnessed unidimensional decline models of aging give way
to life-span developmental models that consider how specific processes and strategies …

Decreased segregation of brain systems across the healthy adult lifespan

MY Chan, DC Park, NK Savalia… - Proceedings of the …, 2014 - National Acad Sciences
Healthy aging has been associated with decreased specialization in brain function. This
characterization has focused largely on describing age-accompanied differences in …

Age-associated cognitive decline

IJ Deary, J Corley, AJ Gow, SE Harris… - British medical …, 2009 - academic.oup.com
Introduction Age-associated cognitive decline—or normal (non-pathological, normative,
usual) cognitive ageing—is an important human experience which differs in extent between …

Enrichment effects on adult cognitive development: can the functional capacity of older adults be preserved and enhanced?

C Hertzog, AF Kramer, RS Wilson… - … science in the public …, 2008 - journals.sagepub.com
In this monograph, we ask whether various kinds of intellectual, physical, and social
activities produce cognitive enrichment effects—that is, whether they improve cognitive …