Alkaloids represent an extensive group of nitrogen-containing secondary metabolites that
are widely distributed throughout the plant kingdom. The pyridine alkaloids of tobacco …

Tobacco (Nicotiana tabacum L.) is a widely cultivated crop of the genus Nicotiana. Due to
the highly addictive nature of tobacco products, tobacco smoking remains the leading cause …

Worldwide, approximately 1.1 billion people are smokers and more than 7 million people die
from the negative effects of smoking every year (WHO report, 2017). One of the main natural …

The model plant Nicotiana benthamiana is an increasingly attractive organism for the
production of high‐value, biologically active molecules. However, N. benthamiana …

More than 8 million deaths are caused by tobacco-related diseases every year. A staggering
1.2 million of those fatalities occur due to second-hand smoke exposure among non …

Alkaloids are important compounds found in Nicotiana plants, essential in plant defense
against herbivores. The main alkaloid of Nicotiana tabacum, nicotine, is produced in roots …

Motivation exists to develop tobacco cultivars with reduced nicotine content for the purpose
of facilitating compliance with expected tobacco product regulations that could mandate the …

In this study, we determined the pyridine alkaloid content (nicotine, nornicotine, anabasine,
anatabine, cotinine, and myosmine) of 58 species and 2 subspecies of the Nicotiana genus …

In leaf and root tissues of Nicotiana tabacum L.(common tobacco), nicotine is by far the
predominant pyridine alkaloid, with anatabine representing only a minor component of the …

The pyridine alkaloid nicotine acts as one of best-studied plant resistant traits in tobacco.
Previous research has shown that NtERF199 and NtERF189, acting as master regulators …