Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrhea in children and
travelers in develo** countries. ETEC is characterized by the ability to produce major …

Diarrhoeal diseases collectively constitute a serious public health challenge globally,
especially as the leading cause of death in children (after respiratory diseases). Childhood …

Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes
substantial morbidity and mortality predominantly in paediatric populations in low-and …

The timelines for develo** vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …

Background Shigellosis is a major cause of moderate to severe diarrhoea and dysentery in
children under 5 years of age in low and middle-income countries. The Flexyn2a vaccine …

Enterotoxigenic Escherichia coli (ETEC) is one of the leading bacterial causes of diarrhoea,
especially among children in low-resource settings, and travellers and military personnel …

Background Vaccine impact and cost-effectiveness models have mostly focused on acute
burden. Shigella-attributable moderate-to-severe diarrhoea has been shown to be …

Summary Background Enterotoxigenic Escherichia coli causes diarrhoea, leading to
substantial mortality and morbidity in children, but no specific vaccine exists. This trial tested …

Shigella is the leading bacterial cause of diarrhoea and the second leading cause of
diarrhoeal mortality among all ages. It also exhibits increasing levels of antibiotic resistance …

Background Shigella is a leading cause of acute watery diarrhea, dysentery, and diarrhea-
attributed linear growth faltering, a precursor to stunting and lifelong morbidity. Several …