Functional status is considered the main determinant of healthy aging. Impairment in
skeletal muscle and the cardiovascular system, two interrelated systems, results in …

Advancing age promotes cardiovascular disease (CVD), the leading cause of death in the
United States and many developed nations. Two major age-related arterial phenotypes …

Physical inactivity is one of the most prevalent major health risk factors, with 8 in 10 US
adults not meeting aerobic and muscle-strengthening guidelines, and is associated with a …

Cardiovascular diseases (CVD) remain the leading cause of morbidity and mortality in both
men and women in developed societies. Age is the greatest risk factor for CVD due largely …

Vascular aging, a determinant factor for cardiovascular disease and health status in the
elderly, is now viewed as a modifiable risk factor. Impaired endothelial vasodilation is a early …

Despite the wealth of epidemiological and experimental studies indicating the protective role
of regular physical activity/exercise training against the sequels of aging and cardiovascular …

Cardiovascular disease (CVD) is the leading cause of death in the United States and aging
is a major risk factor for CVD development. One of the major age-related arterial phenotypes …

Vascular endothelial dysfunction, a characteristic of the aging process, is an important risk
factor for cardiovascular disease in aging. Although, vascular inflammation and oxidative …

Vascular aging, featuring endothelial dysfunction and large elastic artery stiffening, is a
major risk factor for the development of age-associated cardiovascular diseases (CVDs) …

Aging triggers a wide range of cellular and molecular aberrations in the body, giving rise to
inflammation and associated diseases. In particular, aging is associated with persistent low …