The diagnosis and management of nonalcoholic fatty liver disease: practice guidance from the American Association for the Study of Liver Diseases
This guidance provides a data‐supported approach to the diagnostic, therapeutic, and
preventive aspects of nonalcoholic fatty liver disease (NAFLD) care. A “Guidance” document …
preventive aspects of nonalcoholic fatty liver disease (NAFLD) care. A “Guidance” document …
Nonalcoholic fatty liver disease 2020: the state of the disease
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease, with a worldwide
prevalence of 25%. In the United States, NAFLD and its subtype, nonalcoholic …
prevalence of 25%. In the United States, NAFLD and its subtype, nonalcoholic …
The global NAFLD epidemic
NAFLD is a clinical syndrome characterized by predominant macrovesicular steatosis of the
liver. The clinical and histological phenotypes of NAFLD extend from a nonalcoholic fatty …
liver. The clinical and histological phenotypes of NAFLD extend from a nonalcoholic fatty …
[HTML][HTML] Clinical epidemiology and disease burden of nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is defined as the presence of hepatic fat
accumulation after the exclusion of other causes of hepatic steatosis, including other causes …
accumulation after the exclusion of other causes of hepatic steatosis, including other causes …
Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis
NAFLD is a spectrum of progressive liver disease that encompasses simple steatosis,
NASH, fibrosis and, ultimately, cirrhosis. NAFLD is recognized as the hepatic component of …
NASH, fibrosis and, ultimately, cirrhosis. NAFLD is recognized as the hepatic component of …
Triggering and resolution of inflammation in NASH
S Schuster, D Cabrera, M Arrese… - Nature reviews …, 2018 - nature.com
Nonalcoholic steatohepatitis (NASH) is considered the progressive form of nonalcoholic fatty
liver disease (NAFLD) and is characterized by liver steatosis, inflammation, hepatocellular …
liver disease (NAFLD) and is characterized by liver steatosis, inflammation, hepatocellular …
[PDF][PDF] Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis
H Tilg, AR Moschen - Hepatology, 2010 - Wiley Online Library
Whereas in most cases a fatty liver remains free of inflammation, 10%‐20% of patients who
have fatty liver develop inflammation and fibrosis (nonalcoholic steatohepatitis [NASH]) …
have fatty liver develop inflammation and fibrosis (nonalcoholic steatohepatitis [NASH]) …
A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease
NS Abul-Husn, X Cheng, AH Li, Y **n… - … England Journal of …, 2018 - Mass Medical Soc
Background Elucidation of the genetic factors underlying chronic liver disease may reveal
new therapeutic targets. Methods We used exome sequence data and electronic health …
new therapeutic targets. Methods We used exome sequence data and electronic health …
[HTML][HTML] Nonalcoholic fatty liver disease (NAFLD) from pathogenesis to treatment concepts in humans
K Pafili, M Roden - Molecular Metabolism, 2021 - Elsevier
Background Nonalcoholic fatty liver disease (NAFLD) comprises hepatic alterations with
increased lipid accumulation (steatosis) without or with inflammation (nonalcoholic …
increased lipid accumulation (steatosis) without or with inflammation (nonalcoholic …
Non-alcoholic fatty liver disease: metabolic, genetic, epigenetic and environmental risk factors
O Juanola, S Martínez-López, R Francés… - International journal of …, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent causes of chronic liver
disease in the Western world, probably due to the growing prevalence of obesity, metabolic …
disease in the Western world, probably due to the growing prevalence of obesity, metabolic …