Structural determinants and mechanism of HIV-1 genome packaging

K Lu, X Heng, MF Summers - Journal of molecular biology, 2011 - Elsevier
Like all retroviruses, the human immunodeficiency virus selectively packages two copies of
its unspliced RNA genome, both of which are utilized for strand-transfer-mediated …

Structure, replication, and recombination of retrovirus genomes: some unifying hypotheses

JM Coffin - Journal of General Virology, 1979 - microbiologyresearch.org
Retroviruses form a large and diverse group, with isolates from many different vertebrates. In
most cases, our knowledge of the molecular biology of the viruses is derived from one model …

RNA packaging

R Berkowitz, J Fisher, SP Goff - Morphogenesis and maturation of …, 1996 - Springer
RNA Packaging Page 1 RNA Packaging R. BERKOWITZ 1, J. FISHER2, and SP GOFF2
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177 2 Packaging …

Evidence for interstrand quadruplex formation in the dimerization of human immunodeficiency virus 1 genomic RNA.

WI Sundquist, S Heaphy - Proceedings of the National …, 1993 - National Acad Sciences
Retroviruses package two homologous single-stranded RNA genomes within a gag protein-
RNA complex. In mature virion particles, the two RNA strands are thought to associate …

Role of the DIS hairpin in replication of human immunodeficiency virus type 1

B Berkhout, JL Van Wamel - Journal of virology, 1996 - Am Soc Microbiol
The virion-associated genome of human immunodeficiency virus type 1 consists of a
noncovalently linked dimer of two identical, unspliced RNA molecules. A hairpin structure …

Retroviral RNA dimerization: from structure to functions

N Dubois, R Marquet, JC Paillart… - Frontiers in …, 2018 - frontiersin.org
The genome of the retroviruses is a dimer composed by two homologous copies of genomic
RNA (gRNA) molecules of positive polarity. The dimerization process allows two gRNA …

[HTML][HTML] Understanding retroviral life cycle and its genomic RNA packaging

A Chameettachal, F Mustafa, TA Rizvi - Journal of molecular biology, 2023 - Elsevier
Members of the family Retroviridae are important animal and human pathogens. Being
obligate parasites, their replication involves a series of steps during which the virus hijacks …

Map** of poly (A) sequences in the electron microscope reveals unusual structure of type C oncornavirus RNA molecules

W Bender, N Davidson - Cell, 1976 - cell.com
We have synthesized a convenient electron microscope label for map** poly (A)
sequences. Short lengths of poly (dT) are polymerized onto nicked circular SV40 DNA with …

Dimerization of retroviral genomic RNAs: structural and functional implications

JC Paillart, R Marquet, E Skripkin, C Ehresmann… - Biochimie, 1996 - Elsevier
Retroviruses are a family of widespread small animal viruses at the origin of a diversity of
diseases. They share common structural and functional properties such as reverse …

cis elements and trans-acting factors involved in dimer formation of murine leukemia virus RNA

AC Prats, C Roy, PA Wang, M Erard, V Housset… - Journal of …, 1990 - Am Soc Microbiol
The genetic material of all retroviruses examined so far consists of two identical RNA
molecules joined at their 5'ends by the dimer linkage structure (DLS). Since the precise …