Fluorescent probes for ferroptosis bioimaging: advances, challenges, and prospects

J Yin, J Zhan, Q Hu, S Huang, W Lin - Chemical Society Reviews, 2023 - pubs.rsc.org
Ferroptosis is a form of regulatory cell death distinct from caspase-dependent apoptosis and
plays an important role in life entities. Since ferroptosis involves a variety of complex …

Ferroptosis detection: from approaches to applications

F Zeng, S Nijiati, L Tang, J Ye, Z Zhou… - Angewandte …, 2023 - Wiley Online Library
Understanding the intricate molecular machinery that governs ferroptosis and leveraging
this accumulating knowledge could facilitate disease prevention, diagnosis, treatment, and …

Recent advances in small-molecule fluorescent probes for studying ferroptosis

YL Qi, HR Wang, LL Chen, YT Duan… - Chemical Society …, 2022 - pubs.rsc.org
Ferroptosis is an iron-dependent, non-apoptotic form of programmed cell death driven by
excessive lipid peroxidation (LPO). Mounting evidence suggests that the unique modality of …

New anti-cancer explorations based on metal ions

H Hu, Q Xu, Z Mo, X Hu, Q He, Z Zhang… - Journal of …, 2022 - Springer
Due to the urgent demand for more anti-cancer methods, the new applications of metal ions
in cancer have attracted increasing attention. Especially the three kinds of the new mode of …

Recent advance in the development of the fluorescent responsive probes for the study of ferroptosis

B Dong, S Li, Y Wang, X Tang, R Wang, X Kong… - TrAC Trends in …, 2023 - Elsevier
Ferroptosis is an iron-dependent cell death form with the characteristic of the excessive
accumulation of lipid peroxidation. In recent ten years, a host of researches suggested that …

Unexpected dual-functional cyanine fluorophores: NIR multifunctional fluorescent probes for simultaneous monitoring of mitochondrial cysteine/viscosity during kidney …

Y Ye, M He, L Wang, XC Shen, H Chen - Sensors and Actuators B …, 2023 - Elsevier
Cysteine (Cys) level and mitochondrial viscosity are important factors controlling cellular
lipid peroxide metabolism and are closely related to ferroptosis. However, simultaneous …

Ferroptosis as a mechanism of oligodendrocyte loss and demyelination in experimental autoimmune encephalomyelitis

X Li, Y Chu, R Ma, M Dou, S Li, Y Song, Y Lv… - Journal of …, 2022 - Elsevier
Ferroptosis, distinct from necrosis, autophagy and apoptosis, is a unique form of regulated
cell death, and is a potential pathogenic mechanism of neuronal loss and defunction in …

Unique assembly of carbonylpyridinium and chromene reveals mitochondrial thiol starvation under ferroptosis and novel ferroptosis inducer

K Ma, H Yang, T Shen, Y Yue, L Zhao, X Liu, F Huo… - Chemical …, 2022 - pubs.rsc.org
To reveal the delicate function of mitochondria, spatiotemporally precise detection tools
remain highly desirable. However, current probes with positively charged warheads for …

Ferroptosis-driven nanotherapeutics to reverse drug resistance in tumor microenvironment

L Zhu, D Meng, X Wang, X Chen - ACS Applied Bio Materials, 2022 - ACS Publications
Ferroptosis, characterized by iron-dependent lipid reactive oxygen species (ROS)
accumulation, is non-apoptotic programmed cell death highly relevant to tumor …

A controllable self-localized imaging strategy capable of synchronous in situ tracking of local changes in intracellular bioactive small-molecules

K Li, S Xu, B Wang, S Huan, X Song, L Yuan… - Science China …, 2023 - Springer
In situ tracking and localization of ubiquitous bioactive small molecules (BSMs) within their
native habitats is particularly challenging because of their low-molecular weight and …