Endothelial cells lining blood vessels are essential for maintaining vascular homeostasis
and mediate several pathological and physiological processes. Mechanical stresses …

The genomic profile of animal models is not completely matched with the genomic profile of
humans, and 2D cultures do not represent the cellular heterogeneity and tissue architecture …

Preclinical research struggles with its predictive power for drug effects in patients. The
clinical success of preclinically approved drug candidates ranges between 3% and 33 …

Most classical culture models fail to recapitulate the liver microenvironment, lacking the
immune cell and factor interactions linked to regeneration in-vivo. We hypothesize that …

The landscape of cancer treatment has improved over the past decades, aiming to reduce
systemic toxicity and enhance compatibility with the quality of life of the patient. However, at …

Due to its complexity, cancer continues to be one of the leading causes of death worldwide.
The creation of suitable preventative practices and innovative therapies is limited by the lack …

La ingeniería tisular (TE) es un campo científico multidisciplinar emergente que tiene como
objetivo restaurar, mantener o mejorar las funciones de tejidos y órganos. El conocimiento …

Due to its complexity, cancer continues to be one of the leading causes of death worldwide.
The creation of suitable preventative practices and innovative therapies is limited by the lack …

Biosystems are dynamic networks driven by cross-scale interactions between molecules,
cells, tissues, organs and organisms. Recent advances in our understanding of the …