Background Many studies have recently been conducted to assess the antidepressant
efficacy of glutamate modification in mood disorders. This is an update of a review first …

Objective Despite its clinical relevance to pediatric mental health, the relationship of
irritability with anger and aggression remains unclear. We aimed to quantify the …

Irritability is a term used to describe feelings of anger, annoyance and impatience, and is
commonly experienced by individuals in daily life. However, there are diverse …

Background Mental health issues are often associated with poor self-control. Therefore,
effective interventions against mental health problems should include self-control training …

Irritability is a common, impairing, and potentially multifaceted manifestation of
psychopathology. We designed The Irritability and Dysregulation of Emotion Scale (TIDES …

Research into irritability has focused largely on its developmental and child-adolescent
manifestations. Although irritability appears to be as elemental an experience as anxiety or …

Background Irritability is a common symptom in youth that is thought to be predictive of mood
disorders. Its effects on mood are likely to be age-dependent, with direct and indirect …

ABSTRACT Objective We designed The Irritability and Dysregulation of Emotion Scale
(TIDES-13) to test whether irritability consisted of several sub-dimensions that would …

Irritability is a transdiagnostic feature of diverse forms of psychopathology and a rapidly
growing literature implicates the construct in child maladaptation. However, most irritability …

Objective: Although irritability is a widely used term, it has no universal definition. Irritability is
an emotional process that can be defined by a tendency to negative emotional states. No …