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[HTML][HTML] Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions
Polymeric micelles, ie aggregation colloids formed in solution by self-assembling of
amphiphilic polymers, represent an innovative tool to overcome several issues related to …
amphiphilic polymers, represent an innovative tool to overcome several issues related to …
Doxorubicin: nanotechnological overviews from bench to bedside
M Cagel, E Grotz, E Bernabeu, MA Moretton… - Drug discovery today, 2017 - Elsevier
Highlights•Doxorubicin (DOX) is considered one of the most effective chemotherapeutic
agents.•Dose-cumulative cardiotoxicity is the most dangerous adverse effect.•DOX-based …
agents.•Dose-cumulative cardiotoxicity is the most dangerous adverse effect.•DOX-based …
Current status and challenges of analytical methods for evaluation of size and surface modification of nanoparticle-based drug formulations
The present review discusses the current status and difficulties of the analytical methods
used to evaluate size and surface modifications of nanoparticle-based pharmaceutical …
used to evaluate size and surface modifications of nanoparticle-based pharmaceutical …
The new era of nanotechnology, an alternative to change cancer treatment
A Jurj, C Braicu, LA Pop, C Tomuleasa… - Drug design …, 2017 - Taylor & Francis
In the last few years, nanostructures have gained considerable interest for the safe delivery
of therapeutic agents. Several therapeutic approaches have been reported, such as …
of therapeutic agents. Several therapeutic approaches have been reported, such as …
A preparation method for mRNA-LNPs with improved properties
C Geng, K Zhou, Y Yan, C Li, B Ni, J Liu, Y Wang… - Journal of Controlled …, 2023 - Elsevier
The properties of mRNA lipid nanoparticles (mRNA-LNPs), including size, empty particles,
morphology, storage stability, and transfection potency, are critically dependent on the …
morphology, storage stability, and transfection potency, are critically dependent on the …
An integrated assessment of morphology, size, and complement activation of the PEGylated liposomal doxorubicin products Doxil®, Caelyx®, DOXOrubicin, and …
PP Wibroe, D Ahmadvand, MA Oghabian… - Journal of Controlled …, 2016 - Elsevier
In order to improve patient's benefit and safety, comprehensive regulatory guidelines on
specificities of Non-Biological Complex Drugs (NBCDs), such as doxorubicin-encapsulated …
specificities of Non-Biological Complex Drugs (NBCDs), such as doxorubicin-encapsulated …
[HTML][HTML] Size measurement of extracellular vesicles and synthetic liposomes: the impact of the hydration shell and the protein corona
Size characterization of extracellular vesicles (EVs) and drug delivery liposomes is of great
importance in their applications in diagnosis and therapy of diseases. There are many …
importance in their applications in diagnosis and therapy of diseases. There are many …
Drug nanocrystallisation within liposomes
Liposomes are phospholipid bilayer vesicles that have been explored in pharmaceutical
research as drug delivery systems for> 50 years. Despite being important to their …
research as drug delivery systems for> 50 years. Despite being important to their …
Clinical applications of nanomedicine in cancer therapy
M Norouzi, M Amerian, M Amerian, F Atyabi - Drug discovery today, 2020 - Elsevier
Cancer incidence and mortality are rapidly growing worldwide. In attempts to develop more
efficacious therapeutic regimens for patients with cancer, nanomedicines have found …
efficacious therapeutic regimens for patients with cancer, nanomedicines have found …
[HTML][HTML] Structural characterization of biomaterials by means of small angle X-rays and neutron scattering (SAXS and SANS), and light scattering experiments
D Lombardo, P Calandra, MA Kiselev - Molecules, 2020 - mdpi.com
Scattering techniques represent non-invasive experimental approaches and powerful tools
for the investigation of structure and conformation of biomaterial systems in a wide range of …
for the investigation of structure and conformation of biomaterial systems in a wide range of …