The etiology of neuronal development in craniosynostosis: a working hypothesis

ED Brooks, JS Beckett, J Yang… - Journal of …, 2018 - journals.lww.com
Craniosynostosis is one of the most common craniofacial conditions treated by neurologic
and plastic surgeons. In addition to disfigurement, children with craniosynostosis experience …

Glymphatics, cranium, and the brain homeostasis

M Zibitt, V Makhoul, JC Yu, K Nguyen, JK Williams - Face, 2023 - journals.sagepub.com
Despite the human brain accounting for only 2% of total body mass, it consumes 20% of the
body's energy. The average cerebral blood flow, at 70 mL/100 g/minute, is 10x the average …

Clinical staging of craniosynostosis: a call for investigation and collaboration

M Golinko, C Bonfield - Child's Nervous System, 2022 - Springer
Craniosynostosis (CS) is a disease which affects up to 77,000 babies worldwide each year.
Despite the wide phenotypic variation seen in CS (even among the single suture …

Long-term outcomes of non-syndromic and syndromic craniosynostosis: analysis of demographic, morphologic, and surgical factors

T Akai, M Yamashita, T Shiro, S Hamada… - Neurologia medico …, 2022 - jstage.jst.go.jp
In this study, we analyzed the outcomes of patients (followed for 5–38 years, average 17.3
years) with craniosynostosis and evaluated their long-term prognosis. In all, 51 patients who …

The influence of suturectomy on age-related changes in cerebral blood flow in rabbits with familial bicoronal suture craniosynostosis: a quantitative analysis

R Grandhi, GW Peitz, LM Foley, CM Bonfield… - Plos one, 2018 - journals.plos.org
Background Coronal suture synostosis is a condition which can have deleterious physical
and cognitive sequelae in humans if not corrected. A well-established animal model has …

Neurological functional connectivity in unilateral coronal synostosis: a side-based comparison

KE Park, A Singh, C Lacadie, O Allam… - Journal of …, 2021 - journals.lww.com
Purpose: Unicoronal synostosis (UCS) has been associated with reading, language, and
social dysfunction. Limited brain function connectivity studies exist for UCS with none …

Controversies in the Indications for Surgery

JF Yang, D Sasson, J Smetona, JA Persing - Neurosurgical Aspects of …, 2025 - Springer
It has been said “good surgeons know how to operate, better ones when to operate, and the
best, when not to operate.” In addressing the treatment of craniosynostosis, this adage holds …

Systematic Review of the Clinical and Experimental Research Assessing the Effects of Craniosynostosis on the Brain

LMF Furtado, LR Teles… - Journal of …, 2023 - journals.lww.com
Although neurocognitive impairment has been considered as the main argument for the
surgical treatment of craniosynostosis (CS), recent studies reported subtle deficits in …

Brain Disorders Associated with Brachycephaly

C Rusbridge, SP Knowler - Health and Welfare of Brachycephalic …, 2021 - taylorfrancis.com
The skull protects the brain, enables ingestion and respiration, and encloses the visual,
auditory and olfactory systems. The consequences of shortening the box for these essential …

15 Brain Disorders Associated

C Rusbridge, SP Knowler - … A Complete Guide for Veterinary and …, 2021 - books.google.com
Brain disorders of the brachycephalic patient can be broadly divided into conditions that are
directly related to a brachycephalic skull and conditions with suspected inherited tendency …