Epidermal growth factor receptor: key to selective intracellular delivery
Epidermal growth factor receptor (EGFR) is an integral surface protein mediating cellular
response to a number of growth factors. Its overexpression and increased activation due to …
response to a number of growth factors. Its overexpression and increased activation due to …
Principles and applications of single particle tracking in cell research
It is a tough challenge for many decades to decipher the complex relationships between cell
behaviors and cellular physical properties. Single particle tracking (SPT) with high spatial …
behaviors and cellular physical properties. Single particle tracking (SPT) with high spatial …
[HTML][HTML] Endocytosis inhibition in humans to improve responses to ADCC-mediating antibodies
A safe and controlled manipulation of endocytosis in vivo may have disruptive therapeutic
potential. Here, we demonstrate that the anti-emetic/anti-psychotic prochlorperazine can be …
potential. Here, we demonstrate that the anti-emetic/anti-psychotic prochlorperazine can be …
Insight into pyrolysis kinetics of lignocellulosic biomass: isoconversional kinetic analysis by the modified friedman method
Isoconversional methods are commonly used to process the thermogravimetric analysis
(TGA) data and to simultaneously obtain the effective activation energies for lignocellulosic …
(TGA) data and to simultaneously obtain the effective activation energies for lignocellulosic …
Aptamers with tunable affinity enable single‐molecule tracking and localization of membrane receptors on living cancer cells
Tumor cell‐surface markers are usually overexpressed or mutated protein receptors for
which spatiotemporal regulation differs between and within cancers. Single‐molecule …
which spatiotemporal regulation differs between and within cancers. Single‐molecule …
Pyrolysis mechanism and kinetics of high-performance modified lignin-based epoxy resins
X Lu, H Guo, H Que, D Wang, D Liang, T He… - Journal of Analytical and …, 2021 - Elsevier
Lignin used was extracted from the bio-ethanol production residue by enzymatic hydrolysis
method. In this study, a novel lignin-based flame retardant agent (Lig-F) was synthesized by …
method. In this study, a novel lignin-based flame retardant agent (Lig-F) was synthesized by …
Confinement of unliganded EGFR by tetraspanin nanodomains gates EGFR ligand binding and signaling
The epidermal growth factor receptor (EGFR) is a central regulator of cell physiology. EGFR
is activated by ligand binding, triggering receptor dimerization, activation of kinase activity …
is activated by ligand binding, triggering receptor dimerization, activation of kinase activity …
Super-photostable organic dye for long-term live-cell single-protein imaging
Organic dyes play a crucial role in live-cell imaging because of their advantageous
properties, such as photostability and high brightness. Here we introduce a super …
properties, such as photostability and high brightness. Here we introduce a super …
Dimerization of β2-adrenergic receptor is responsible for the constitutive activity subjected to inverse agonism
Dimerization of beta 2-adrenergic receptor (β 2-AR) has been observed across various
physiologies. However, the function of dimeric β 2-AR is still elusive. Here, we revealed that …
physiologies. However, the function of dimeric β 2-AR is still elusive. Here, we revealed that …
A comparative study on heterogeneity of clay rocks using pore‐scale diffusion simulations and experiments
Accurate modeling and simulation of radionuclide migration in clay rocks such as the
Opalinus Clay (OPA) play a key role in the safety assessment of deep geological …
Opalinus Clay (OPA) play a key role in the safety assessment of deep geological …