A review of alpha-glucosidase inhibitors from plants as potential candidates for the treatment of type-2 diabetes

AM Dirir, M Daou, AF Yousef, LF Yousef - Phytochemistry Reviews, 2022 - Springer
Diabetes mellitus is a multifactorial global health disorder that is rising at an alarming rate.
Cardiovascular diseases, kidney damage and neuropathy are the main cause of high …

Aloe vera and Streptozotocin-Induced Diabetes Mellitus

F Haghani, MR Arabnezhad, S Mohammadi… - Revista Brasileira de …, 2022 - Springer
Diabetes mellitus is defined as prolonged hyperglycemia, which can harm the eyes, kidneys,
and cardiovascular and neurological systems. Herbal agents and their derived supplements …

[HTML][HTML] Therapeutic emergence of rhein as a potential anticancer drug: a review of its molecular targets and anticancer properties

S Henamayee, K Banik, BL Sailo, B Shabnam… - Molecules, 2020 - mdpi.com
According to the World Health Organization (WHO), cancer is the second-highest cause of
mortality in the world, and it kills nearly 9.6 million people annually. Besides the fatality of the …

Aloe emodin-conjugated sulfonyl hydrazones as novel type of antibacterial modulators against S. aureus 25923 through multifaceted synergistic effects

Z Deng, RRY Bheemanaboina, Y Luo, CH Zhou - Bioorganic Chemistry, 2022 - Elsevier
Aloe emodin-conjugated sulfonyl hydrazones were designed and synthesized as novel type
of antibacterial modulators. Aloe emodin benzenesulfonyl hydrazone 5a (AEBH-5a) was …

Emodin accelerates diabetic wound healing by promoting anti-inflammatory macrophage polarization

C Chen, Z Lin, W Liu, Q Hu, J Wang, X Zhuang… - European Journal of …, 2022 - Elsevier
Diabetic wound healing, characterized by chronic inflammation, remains a medical
challenge. The failure of prompt conversion from pro-inflammatory M1-like macrophage to …

Plant anthraquinones: classification, distribution, biosynthesis, and regulation

P Wang, J Wei, X Hua, G Dong… - Journal of Cellular …, 2024 - Wiley Online Library
Anthraquinones are polycyclic compounds with an unsaturated diketone structure (quinoid
moiety). As important secondary metabolites of plants, anthraquinones play an important …

Potential antidiabetic phytochemicals in plant roots: a review of in vivo studies

H Ardalani, F Hejazi Amiri, A Hadipanah… - Journal of Diabetes & …, 2021 - Springer
Background Medicinal plants are used to treat various disorders, including diabetes,
globally in a range of formulations. While attention has mainly been on the aerial plant parts …

Update on pharmacological activities, security, and pharmacokinetics of rhein

GM Li, JR Chen, HQ Zhang, XY Cao… - Evidence‐Based …, 2021 - Wiley Online Library
Rhein, belonging to anthraquinone compounds, is one of the main active components of
rhubarb and Polygonum multiflorum. Rhein has a variety of pharmacological effects, such as …

Recent applications of magnetic solid phase extraction in sample preparation for phytochemical analysis

SJ Yin, J Zhao, FQ Yang - Journal of Pharmaceutical and Biomedical …, 2021 - Elsevier
Sample preparation such as isolation and pre-concentration is a crucial step for the
phytochemical analysis. Magnetic solid-phase extraction (MSPE) has received considerable …

[HTML][HTML] Effects of anthraquinones on immune responses and inflammatory diseases

D **n, H Li, S Zhou, H Zhong, W Pu - Molecules, 2022 - mdpi.com
The anthraquinones (AQs) and derivatives are widely distributed in nature, including plants,
fungi, and insects, with effects of anti-inflammation and anti-oxidation, antibacterial and …